Trial reportQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2014
Predictors of health-related quality of life changes after lifestyle intervention in persons at risk of type 2 diabetes mellitus.
Trial report in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Participant Characteristics Associated with Changes in Mental Health in a Trial of Behavioural Weight Management Programmes: Secondary Analysis of the WRAP Trial.Obesity facts · 2022Trial
- Valuing a Lifestyle Intervention for Middle Eastern Immigrants at Risk of Diabetes.International journal of environmental research and public health · 2018Trial
- Design and baseline characteristics of the PerfectFit study: a multicenter cluster-randomized trial of a lifestyle intervention in employees with increased cardiovascular risk.BMC public health · 2015Trial
- Health-related quality of life changes in patients with Q-fever fatigue syndrome: a four-year follow-up study, 10 years post-infection.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Observational
- Impaired health-related quality of life due to elevated risk of developing diabetes: A cross-sectional study in Indonesia.PloS one · 2023Article
- Activate Your Health, a 3-year, multi-site, workplace healthy lifestyle promotion program: study design.BMC public health · 2019Article
- Measurement properties and normative data for the Norwegian SF-36: results from a general population survey.Health and quality of life outcomes · 2017Article
- Article
- Health-related quality of life in two randomized controlled trials of phentermine/topiramate for obesity: What mediates improvement?Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2016Article
- Combined association of fitness and central adiposity with health-related quality of life in healthy Men: a cross-sectional study.Health and quality of life outcomes · 2015Article
- Identification of Risk Factors Affecting Impaired Fasting Glucose and Diabetes in Adult Patients from Northeast China.International journal of environmental research and public health · 2015Article
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Authors and funding
4 authors.
Funding
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Abstract
purposeTo assess health-related quality of life (HRQOL) of subjects at risk of type 2 diabetes undergoing lifestyle intervention, and predictors for improved HRQOL.
methodsThe Finnish Diabetes Risk Score was used by general practitioners to identify individuals at risk. Low-intensity interventions with an 18-month follow-up were employed. HRQOL was assessed using the SF-36 at baseline and compared with results from a general Norwegian population survey and further at 6 and 18 months. Simple and multiple linear regression analyses were applied to identify predictors of changes in HRQOL of clinical importance.
resultsTwo hundred and thirteen participants (50 % women; mean age: 46 years, mean body mass index: 37) were included: 182 returned for 18-month follow-up, of whom 172 completed the HRQOL questionnaire. HRQOL was reduced with clinical significance compared with general Norwegians. The mean changes in HRQOL from the baseline to the follow-up were not of clinical importance. However, one out of three individuals achieved a moderate or large clinical improvement in HRQOL. The best determinant for improved HRQOL was obtained for a composite, clinically significant lifestyle change, i.e. both a weight reduction of at least 5 % and an improvement in exercise capacity of at least 10 %, which was associated with an improvement in five out of the eight SF-36 domains.
conclusionSubjects at risk of type 2 diabetes report a clinically important reduction in HRQOL compared with general Norwegians. The best predictor of improved HRQOL was a small weight loss combined with a small improvement in aerobic capacity.
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