ArticlePloS one2014
Ontology for the asexual development and anatomy of the colonial chordate Botryllus schlosseri.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 59 citations in OpenAlex.
- Multi-stage single-cell atlas of a chordate non-embryonic development unveils dedifferentiating bud founder cells.Nature communications · 2026Article
- First chromosome-level genome assembly of the colonial chordate model Botryllus schlosseri (Tunicata).GigaScience · 2025Article
- Speed vs completeness: a comparative study of solitary and colonial tunicate embryogenesis.Frontiers in cell and developmental biology · 2025Article
- The novel Orshina Rhythm in a colonial urochordate signifies the display of recurrent aging/rejuvenation sequels.Scientific reports · 2023Article
- Multiple Forms of Neural Cell Death in the Cyclical Brain Degeneration of A Colonial Chordate.Cells · 2023Article
- Contributions from both the brain and the vascular network guide behavior in the colonial tunicate Botryllus schlosseri.The Journal of experimental biology · 2022Article
- Yamanaka Factors in the Budding TunicateFrontiers in cell and developmental biology · 2022Article
- The Onset of Whole-Body Regeneration inFrontiers in cell and developmental biology · 2022Article
- Article
- Review
- Sexual and asexual development: two distinct programs producing the same tunicate.Cell reports · 2021Article
- The Ontology of the Amphioxus Anatomy and Life Cycle (AMPHX).Frontiers in cell and developmental biology · 2021Article
- The ontology of the anatomy and development of the solitary ascidian Ciona: the swimming larva and its metamorphosis.Scientific reports · 2020Article
- Integrin-alpha-6+ Candidate stem cells are responsible for whole body regeneration in the invertebrate chordate Botrylloides diegensis.Nature communications · 2020Article
- ANISEED 2019: 4D exploration of genetic data for an extended range of tunicates.Nucleic acids research · 2020Article
- Review
- Article
- Differentiation and Induced Sensorial Alteration of the Coronal Organ in the Asexual Life of a Tunicate.Integrative and comparative biology · 2018Article
- Convergent Acquisition of Nonembryonic Development in Styelid Ascidians.Molecular biology and evolution · 2018Article
- Identification of differentially expressed genes from multipotent epithelia at the onset of an asexual development.Scientific reports · 2016Article
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Authors and funding
8 authors at 3 institutions in 3 countries.
Funding
Abstract
Ontologies provide an important resource to integrate information. For developmental biology and comparative anatomy studies, ontologies of a species are used to formalize and annotate data that are related to anatomical structures, their lineage and timing of development. Here, we have constructed the first ontology for anatomy and asexual development (blastogenesis) of a bilaterian, the colonial tunicate Botryllus schlosseri. Tunicates, like Botryllus schlosseri, are non-vertebrates and the only chordate taxon species that reproduce both sexually and asexually. Their tadpole larval stage possesses structures characteristic of all chordates, i.e. a notochord, a dorsal neural tube, and gill slits. Larvae settle and metamorphose into individuals that are either solitary or colonial. The latter reproduce both sexually and asexually and these two reproductive modes lead to essentially the same adult body plan. The Botryllus schlosseri Ontology of Development and Anatomy (BODA) will facilitate the comparison between both types of development. BODA uses the rules defined by the Open Biomedical Ontologies Foundry. It is based on studies that investigate the anatomy, blastogenesis and regeneration of this organism. BODA features allow the users to easily search and identify anatomical structures in the colony, to define the developmental stage, and to follow the morphogenetic events of a tissue and/or organ of interest throughout asexual development. We invite the scientific community to use this resource as a reference for the anatomy and developmental ontology of B. schlosseri and encourage recommendations for updates and improvements.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.