Evidence map›Paper›PMID 24789206›Full record

ReviewAmerican journal of physiology. Gastrointestinal and liver physiology2014

Chemoprevention in gastrointestinal physiology and disease. Natural products and microbiome.

Allen K Greiner, Rao V L Papineni, Shahid Umar

Abstract readReview
In one paragraph

Review in American journal of physiology. Gastrointestinal and liver physiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Trial
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Mutual Two-Way Interactions of Curcumin and Gut Microbiota.International journal of molecular sciences · 2020
    Review
  13. Review
  14. Review
  15. Human Gut Microbiota and Gastrointestinal Cancer.Genomics, proteomics & bioinformatics · 2018
    Review
  16. The skin microbiome and immune system: Potential target for chemoprevention?Photodermatology, photoimmunology & photomedicine · 2018
    Review
  17. Review
  18. Article
  19. Cautiously using natural medicine to treat liver problems.World journal of gastroenterology · 2017
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Allen K GreinerDepartments of Molecular and Integrative Physiology and Family Medicine Research Division, University of Kansas Medical Center, Kansas City, Kansas;
Rao V L PapineniDepartments of Molecular and Integrative Physiology and Family Medicine Research Division, University of Kansas Medical Center, Kansas City, Kansas; PACT and Health, Branford, Connecticut; and Precision X-Ray Inc., North Branford, Connecticut.
Shahid UmarDepartments of Molecular and Integrative Physiology and Family Medicine Research Division, University of Kansas Medical Center, Kansas City, Kansas; sumar@kumc.edu.

Funding

Beta-Catenin/NF-kB in Hyperplasia/Neoplasia of Colonic Crypts: ChemopreventionR01CA131413 · NCI · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI UMAR, SHAHID · 2008 to 2011
$1.2M
NCI NIH HHS R01 CA131413NCI NIH HHS R01-CA-131413
6 · The paper itself

Abstract

The human intestinal tract harbors a complex ecosystem of commensal bacteria that play a fundamental role in the well-being of their host. There is a general consensus that diet rich in plant-based foods has many advantages in relation to the health and well-being of an individual. In adults, diets that have a high proportion of fruit and vegetables and a low consumption of meat are associated with a highly diverse microbiota and are defined by a greater abundance of Prevotella compared with Bacteroides, whereas the reverse is associated with a diet that contains a low proportion of plant-based foods. In a philosophical term, our consumption of processed foods, widespread use of antibiotics and disinfectants, and our modern lifestyle may have forever altered our ancient gut microbiome. We may never be able to identify or restore our microbiomes to their ancestral state, but dietary modulation to manipulate specific gut microbial species or groups of species may offer new therapeutic approaches to conditions that are prevalent in modern society, such as functional gastrointestinal disorders, obesity, and age-related nutritional deficiency. We believe that this will become an increasingly important area of health research.

Indexed as

DietLife StyleMicrobiotaRisk Reduction BehaviorAnimalsAnti-Bacterial AgentsChemopreventionDisinfectantsDysbiosisFruitGastrointestinal DiseasesGastrointestinal TractHost-Pathogen InteractionsHumansMeatPhytochemicalsAnti-Bacterial AgentsDisinfectantsPhytochemicalscolon cancerdysbiosisgastrointestinal tractmicrobiotanatural products

Identifiers

PMID24789206
PMCPMC4080166

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.