ArticleGenetics2014
Gene-flow in a mosaic hybrid zone: is local introgression adaptive?
Article in Genetics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 76 citations in OpenAlex.
- No effect of interspecific thermal tolerance on the stability of a blue mussel, Mytilus sp., hybrid zone.Scientific reports · 2026Article
- Population Genomics and Connectivity of the Blue Mussel Species Complex: Insights From a North-East Atlantic Hybrid Zone.Evolutionary applications · 2025Article
- Replicate geographic transects across a hybrid zone reveal parallelism and differences in the genetic architecture of reproductive isolation.Evolution letters · 2025Article
- Anthropogenic noise exposure suppresses the immune response inFrontiers in immunology · 2025Article
- Genomic Introgression Between Critically Endangered and Stable Species of Darwin's Tree Finches on the Galapagos Islands.Evolutionary applications · 2025Article
- Monitoring the genetic diversity in holothurian populations from the Italian coasts with mitochondrial DNA sequences.Scientific reports · 2024Article
- A chromosome-scale Mytilus edulis genome assembly for aquaculture, marine ecology, and evolution.G3 (Bethesda, Md.) · 2024Article
- Integration of natural selection across the life cycle stabilizes a marine mussel hybrid zone.Ecology and evolution · 2024Article
- Different patterns of introgression in a three species hybrid zone among European cave salamanders.Ecology and evolution · 2023Article
- Balancing selection and candidate loci for survival and growth during larval development in the Mediterranean mussel, Mytilus galloprovincialis.G3 (Bethesda, Md.) · 2023Article
- Genetic parallelism between European flat oyster populations at the edge of their natural range.Evolutionary applications · 2023Article
- Genetic and morphological data demonstrate hybridization and backcrossing in a pair of salamanders at the far end of the speciation continuum.Evolutionary applications · 2021Article
- Hybridization Dynamics and Extensive Introgression in the Daphnia longispina Species Complex: New Insights from a High-Quality Daphnia galeata Reference Genome.Genome biology and evolution · 2021Article
- Inferring Adaptive Introgression Using Hidden Markov Models.Molecular biology and evolution · 2021Article
- Population genomics and history of speciation reveal fishery management gaps in two related redfish species (Evolutionary applications · 2021Article
- Introduction to Population Genomics Methods.Methods in molecular biology (Clifton, N.J.) · 2021Article
- The contribution of ancient admixture to reproductive isolation between European sea bass lineages.Evolution letters · 2020Article
- Twin introductions by independent invader mussel lineages are both associated with recent admixture with a native congener in Australia.Evolutionary applications · 2020Article
- Selective sweeps on novel and introgressed variation shape mimicry loci in a butterfly adaptive radiation.PLoS biology · 2020Article
- Marine stepping-stones: Connectivity of Mytilus edulis populations between offshore energy installations.Molecular ecology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Genome-wide scans of genetic differentiation between hybridizing taxa can identify genome regions with unusual rates of introgression. Regions of high differentiation might represent barriers to gene flow, while regions of low differentiation might indicate adaptive introgression-the spread of selectively beneficial alleles between reproductively isolated genetic backgrounds. Here we conduct a scan for unusual patterns of differentiation in a mosaic hybrid zone between two mussel species, Mytilus edulis and M. galloprovincialis. One outlying locus, mac-1, showed a characteristic footprint of local introgression, with abnormally high frequency of edulis-derived alleles in a patch of M. galloprovincialis enclosed within the mosaic zone, but low frequencies outside of the zone. Further analysis of DNA sequences showed that almost all of the edulis allelic diversity had introgressed into the M. galloprovincialis background in this patch. We then used a variety of approaches to test the hypothesis that there had been adaptive introgression at mac-1. Simulations and model fitting with maximum-likelihood and approximate Bayesian computation approaches suggested that adaptive introgression could generate a "soft sweep," which was qualitatively consistent with our data. Although the migration rate required was high, it was compatible with the functioning of an effective barrier to gene flow as revealed by demographic inferences. As such, adaptive introgression could explain both the reduced intraspecific differentiation around mac-1 and the high diversity of introgressed alleles, although a localized change in barrier strength may also be invoked. Together, our results emphasize the need to account for the complex history of secondary contacts in interpreting outlier loci.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.