ArticleAJNR. American journal of neuroradiology2014
Variation in anisotropy and diffusivity along the medulla oblongata and the whole spinal cord in adolescent idiopathic scoliosis: a pilot study using diffusion tensor imaging.
Article in AJNR. American journal of neuroradiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Neurophysiological, balance and motion evidence in adolescent idiopathic scoliosis: A systematic review.PloS one · 2024Pooled it
- Preoperative Neurological and Neurophysiological Assessment of Patients with Idiopathic Scoliosis Treated or Not Treated with Physiotherapy: A Retrospective Comparative Study.Brain sciences · 2026Article
- Neuromorphological Alterations in the Somatosensory System of Adolescent Idiopathic Scoliosis: A Systematic Review of Magnetic Resonance Imaging Studies.Children (Basel, Switzerland) · 2026Review
- The Neurogenic Abnormities of Paraspinal Muscles Lead to Asymmetry of Fibre Types in Adolescent Idiopathic Scoliosis.Journal of cellular and molecular medicine · 2025Article
- Cerebral White Matter Connectivity in Adolescent Idiopathic Scoliosis: A Diffusion Magnetic Resonance Imaging Study.Children (Basel, Switzerland) · 2022Article
- Association of Ligamentum Flavum Hypertrophy with Adolescent Idiopathic Scoliosis Progression-Comparative Microarray Gene Expression Analysis.International journal of molecular sciences · 2022Article
- Are craniocervical angulations or syrinx risk factors for the initiation and progression of scoliosis in Chiari malformation type I?Neurosurgical review · 2021Article
- Transcriptome Regulation by Oncogenic ALK Pathway in Mammalian Cortical Development Revealed by Single-Cell RNA Sequencing.Cerebral cortex (New York, N.Y. : 1991) · 2021Article
- Rescue of maternal immune activation-induced behavioral abnormalities in adult mouse offspring by pathogen-activated maternal TNature neuroscience · 2021Article
- Quasi-automatic early detection of progressive idiopathic scoliosis from biplanar radiography: a preliminary validation.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2019Article
- Altered White Matter Microstructure in the Corpus Callosum and Its Cerebral Interhemispheric Tracts in Adolescent Idiopathic Scoliosis: Diffusion Tensor Imaging Analysis.AJNR. American journal of neuroradiology · 2018Article
- Abnormal PITX1 gene methylation in adolescent idiopathic scoliosis: a pilot study.BMC musculoskeletal disorders · 2018Article
- Automatic brain tissue segmentation based on graph filter.BMC medical imaging · 2018Article
- Etiological Theories of Adolescent Idiopathic Scoliosis: Past and Present.The open orthopaedics journal · 2017Review
- Electrophysiological and histological changes of paraspinal muscles in adolescent idiopathic scoliosis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2016Article
- Bi-planar spinal stereoradiography of adolescent idiopathic scoliosis: considerations in 3D alignment and functional balance.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2016Article
- Noise reduction of diffusion tensor images by sparse representation and dictionary learning.Biomedical engineering online · 2016Article
- Adolescent idiopathic scoliosis (AIS): a multifactorial cascade concept for pathogenesis and embryonic origin.Scoliosis and spinal disorders · 2016Review
- Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeDisturbed somatosensory evoked potentials have been demonstrated in patients with adolescent idiopathic scoliosis (but this functional delay was found to originate above the C5-6 level, while the lower cord level was unaffected). Together with MR imaging observation of tonsillar ectopia and a relatively tethered cord, we hypothesized that there is disturbed mean diffusivity integrity along the spinal cord. In this study, advanced DTI was used to evaluate whether there was underlying decreased WM integrity within the brain stem and spinal cord in adolescent idiopathic scoliosis and any relationship to cerebellar tonsillar ectopia. Clinical impact on balance testing was also correlated. MATERIALS AND
methodsThirteen girls with adolescent idiopathic scoliosis with right thoracic curves were compared with 13 age-matched healthy girls. DTI of the brain and whole spinal cord was performed. ROIs were manually defined for the medulla oblongata and along each intervertebral segment of the cord. Mean values of fractional anisotropy and mean diffusivity were computed at the defined regions. Between-group comparisons were performed by 1-way ANOVA.
resultsSignificantly decreased fractional anisotropy values and increased mean diffusivity values were found at the medulla oblongata and C1-2, C2-3, C3-4, and C4-5 segments in patients with adolescent idiopathic scoliosis compared with healthy subjects. No significant difference was found in the lower cord levels. Significant correlation was found between the tonsillar level and fractional anisotropy value at the C4-5 level in patients with adolescent idiopathic scoliosis only.
conclusionsThe findings from this study are in agreement with previous findings showing abnormal somatosensory evoked potential readings occurring only above the C5-6 level in patients with adolescent idiopathic scoliosis; these findings might partially explain the pathophysiology of the neural pathway involved.
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