ArticleBMJ (Clinical research ed.)2014
Physical capability in mid-life and survival over 13 years of follow-up: British birth cohort study.
Article in BMJ (Clinical research ed.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 88 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
88 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Effects of Concurrent Strength and Endurance Training on Measures of Physical Fitness in Healthy Middle-Aged and Older Adults: A Systematic Review with Meta-Analysis.Sports medicine (Auckland, N.Z.) · 2023Pooled it
- Association of Back Pain with Mortality: a Systematic Review and Meta-analysis of Cohort Studies.Journal of general internal medicine · 2021Pooled it
- The effects of same-session combined exercise training on cardiorespiratory and functional fitness in older adults: a systematic review and meta-analysis.Aging clinical and experimental research · 2019Pooled it
- Analyzing feed-forward loop relationship in aging phenotypes: physical activity and physical performance.Mechanisms of ageing and developmentTrial
- Prevalence and direct costs of vestibular disease in France - matched case-control study results from the 2022 and 2023 french health data system.Cost effectiveness and resource allocation : C/E · 2026Article
- Midlife aging and performance study (MAPS): evaluating biological aging through a physical capacity battery.GeroScience · 2026Article
- Article
- Sarcopenia and mortality in Indigenous and non-Indigenous New Zealand octogenarians-the LiLACS NZ cohort study.European geriatric medicine · 2025Article
- The interplay between perceived fatigability, intrinsic capacity, and physical activity: network analysis in a British birth cohort study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025Article
- Low sensory responsiveness is associated with accelerated aging in midlife.Scientific reports · 2025Article
- Physical Function Changes in Older Adults Living in Temporary Housing after the Great East Japan Earthquake.JMA journal · 2025Article
- Spousal bereavement and its effects on later life physical and cognitive capability: the Tromsø study.GeroScience · 2024Article
- Sarcopenia.Nature reviews. Disease primers · 2024Review
- Article
- Sarcopenia prevalence using handgrip strength or chair stand performance in adults living with type 2 diabetes mellitus.Age and ageing · 2024Article
- A molecular index for biological age identified from the metabolome and senescence-associated secretome in humans.Aging cell · 2024Article
- Mortality and disability risk among older adults unable to complete grip strength and physical performance tests: a population-based cohort study from China.BMC public health · 2024Article
- The physiological and physical benefits of two types of concurrent training: a randomized controlled trial.BMC sports science, medicine & rehabilitation · 2024Article
- Comparing associations of handgrip strength and chair stand performance with all-cause mortality-implications for defining probable sarcopenia: the Tromsø Study 2015-2020.BMC medicine · 2023Article
- Prediabetes Progression and Regression on Objectively- Measured Physical Function: A Prospective Cohort Study.Diabetes & metabolism journal · 2023Article
28 more citing papers are in PubMed but not listed here.
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5 authors.
Funding
Abstract
objectivesTo examine associations between three commonly used objective measures of physical capability assessed at age 53 and a composite score of these measures and all cause mortality; to investigate whether being unable to perform these tests is associated with mortality.
designCohort study.
settingMRC National Survey of Health and Development in England, Scotland, and Wales.
participants1355 men and 1411 women with data on physical capability at age 53 who were linked to the National Health Service (NHS) central register for death notification.
main outcome measureAll cause mortality between ages 53 (1999) and 66 (2012).
resultsFor each of the three measures of physical capability (grip strength, chair rise speed, and standing balance time) those participants unable to perform the test and those in the lowest performing fifth were found to have higher mortality rates than those in the highest fifth. Adjustment for baseline covariates partially attenuated associations but in fully adjusted models the main associations remained. For example, the fully adjusted hazard ratio of all cause mortality for the lowest compared with the highest fifth of a composite score of physical capability was 3.68 (95% confidence interval 2.03 to 6.68). Those people who could not perform any of the tests had considerably higher rates of death compared with those people able to perform all three tests (8.40, 4.35 to 16.23). When a series of models including different combinations of the measures were compared by using likelihood ratio tests, all three measures of physical capability were found to improve model fit, and a model including all three measures produced the highest estimate of predictive ability (Harrell's C index 0.71, 95% confidence interval 0.65 to 0.77). There was some evidence that standing balance time was more strongly associated with mortality than the other two measures.
conclusionsLower levels of physical capability at age 53 and inability to perform capability tests are associated with higher rates of mortality. Even at this relatively young age these measures identify groups of people who are less likely than others to achieve a long and healthy life.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.