Evidence map›Paper›PMID 24786908›Full record

ArticleActa orthopaedica2014

Age- and health-related quality of life after total hip replacement: decreasing gains in patients above 70 years of age.

Max Gordon, Meridith Greene, Paolo Frumento, Ola Rolfson, Göran Garellick, André Stark

Abstract readComparative Study
In one paragraph

Article in Acta orthopaedica, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  17. Mid-term clinical results of the cementless R3 cup and Polarstem total hip arthroplasty.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2019
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Max GordonThe Swedish Hip Arthroplasty Register , Gothenburg.
Meridith Greene
Paolo Frumento
Ola Rolfson
Göran Garellick
André Stark

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhile age is a common confounder, its impact on health-related quality of life (HRQoL) after total hip replacement is uncertain. This could be due to improper statistical modeling of age in previous studies, such as treating age as a linear variable or by using age categories. We hypothesized that there is a non-linear association between age and HRQoL.

methodsWe selected a nationwide cohort from the Swedish Hip Arthroplasty Register of patients operated with total hip replacements due to primary osteoarthritis between 2008 and 2010. For estimating HRQoL, we used the generic health outcome questionnaire EQ-5D of the EuroQol group that consits or 2 parts: the EQ-5D index and the EQ VAS estimates. Using linear regression, we modeled the EQ-5D index and the EQ VAS against age 1 year after surgery. Instead of using a straight line for age, we applied a method called restricted cubic splines that allows the line to bend in a controlled manner. Confounding was controlled by adjusting for preoperative HRQoL, sex, previous contralateral hip surgery, pain, and Charnley classification.

resultsComplete data on 27,245 patients were available for analysis. Both the EQ-5D index and EQ VAS showed a non-linear relationship with age. They were fairly unaffected by age until the patients were in their late sixties, after which age had a negative effect.

interpretationThere is a non-linear relationship between age and HRQoL, with improvement decreasing in the elderly.

Indexed as

Health StatusAgedAged, 80 and overAgingArthroplasty, Replacement, HipCohort StudiesFemaleHumansLinear ModelsMaleOsteoarthritis, HipPain MeasurementQuality of LifeRegistriesSurveys and QuestionnairesSweden

Identifiers

PMID24786908
PMCPMC4062790

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.