ArticleOrganic letters2014
Dual C-H functionalization of N-aryl amines: synthesis of polycyclic amines via an oxidative Povarov approach.
Article in Organic letters, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Diastereoselective multicomponent synthesis of dihydroisoindolo[2,1-RSC advances · 2023Article
- Borane-catalyzed cascade Friedel-Crafts alkylation/[1,5]-hydride transfer/Mannich cyclization to afford tetrahydroquinolines.Chemical science · 2022Article
- Synthesis of the Hexahydropyrrolo-[3,2-c]-quinoline Core Structure and Strategies for Further Elaboration to Martinelline, Martinellic Acid, Incargranine B, and Seneciobipyrrolidine.Molecules (Basel, Switzerland) · 2021Review
- Oxidative Asymmetric Formal Aza-Diels⁻Alder Reactions of Tetrahydro-β-carboline with Enones in the Synthesis of Indoloquinolizidine-2-ones.Molecules (Basel, Switzerland) · 2018Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Iminium ions generated in situ via copper(I) bromide catalyzed oxidation of N-aryl amines readily undergo [4 + 2] cycloadditions with a range of dienophiles. This method involves the functionalization of both a C(sp(3))-H and a C(sp(2))-H bond and enables the rapid construction of polycyclic amines under relatively mild conditions.
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Registered trials
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