ArticleInternational journal of molecular sciences2014
Antenna-specific glutathione S-transferase in male silkmoth Bombyx mori.
Article in International journal of molecular sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 42 citations in OpenAlex.
- Identification and Characterization of the Detoxification Genes from the Transcriptome ofInsects · 2026Article
- Detoxification Metabolic Adaptation ofInsects · 2026Article
- Odorant degrading enzyme candidates enriched in the antennae of the white-spotted flower chafer,Frontiers in insect science · 2026Article
- Article
- Role of Insect and Mammal Glutathione Transferases in Chemoperception.Biomolecules · 2023Review
- Transcriptomic Identification and Expression Profile Analysis of Odorant-Degrading Enzymes from the Asian Corn Borer Moth,Insects · 2022Article
- Article
- Functional and Structural Diversity of Insect Glutathione S-transferases in Xenobiotic Adaptation.International journal of biological sciences · 2022Review
- Antennae-abundant expression of candidate cytochrome P450 genes associated with odorant degradation in the asian citrus psyllid,Frontiers in physiology · 2022Article
- Identification and Characterization of an Antennae-Specific Glutathione S-Transferase From the Indian Meal Moth.Frontiers in physiology · 2021Article
- Gas Chromatography-Mass Spectrometry Based Midgut Metabolomics Reveals the Metabolic Perturbations under NaF Stress inInsects · 2019Article
- Antennal transcriptome analyses and olfactory protein identification in an important wood-boring moth pest, Streltzoviella insularis (Lepidoptera: Cossidae).Scientific reports · 2019Article
- Cloning, phylogenetic research, and prokaryotic expression study of the metabolic detoxification genePeerJ · 2019Article
- Multiple Glutathione S-Transferase Genes in Heortia vitessoides (Lepidoptera: Crambidae): Identification and Expression Patterns.Journal of insect science (Online) · 2018Article
- Glutathione-S-Transferases in the Olfactory Organ of the Noctuid MothFrontiers in physiology · 2018Article
- Identification, Expression, and Regulation of an Omega Class Glutathione S-transferase inFrontiers in physiology · 2018Article
- Deciphering the olfactory repertoire of the tiger mosquito Aedes albopictus.BMC genomics · 2017Article
- Tick Haller's Organ, a New Paradigm for Arthropod Olfaction: How Ticks Differ from Insects.International journal of molecular sciences · 2017Article
- Proteomic Analysis of Silkworm Antennae.Journal of chemical ecology · 2015Article
- Identification of Putative Carboxylesterase and Glutathione S-transferase Genes from the Antennae of the Chilo suppressalis (Lepidoptera: Pyralidae).Journal of insect science (Online) · 2015Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Glutathione S-transferases (GSTs) are multifunctional enzymes that are widely distributed in different species. GSTs detoxify exogenous and endogenous substances by conjugation to reduced glutathione. We characterized BmGSTD4, an antenna-specific GST, in male silkmoths. The full-length mRNA of Bmgstd4 was cloned by RACE-PCR and contained an open reading frame of 738 bp encoding a 245 amino acid protein. The antenna specificity of BmGSTD4 was validated at the mRNA and protein levels and BmGSTD4 was shown to localize in the sensillum of male silkmoth antennae. Homology modeling and multi-sequence alignment suggested that BmGSTD4 was a typical GST belonging to the δ class and had a canonical GST fold with a conserved N-terminus, including a glutathione-binding site and a C-terminal domain harboring a hydrophobic substrate-binding site. Restricted expression of BmGSTD4 in silkmoth antennae combined with GST activity suggested that BmGSTD4 was involved in the detoxification of harmful chemicals.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.