ArticleInternational journal of impotence research
Dracaena arborea extracts delay the pro-ejaculatory effect of dopamine and oxytocin in spinal male rats.
Article in International journal of impotence research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 16 citations in OpenAlex.
- Dracaena arborea improves sperm characteristics and antioxidant enzymes in adult male rats with experimental varicocele.JBRA assisted reproduction · 2021Article
- Effect of Herbal Medicine on Fertility Potential in Experimental Animals - an Update Review.Materia socio-medica · 2020Review
- Aphrodisiac property of aqueous and methanolic extracts ofInternational journal of reproductive biomedicine · 2019Article
- Guibourtia tessmannii-induced fictive ejaculation in spinal male rat: involvement of DPharmaceutical biology · 2017Article
- Aphrodisiac Activity of the Aqueous Crude Extract of Purple Corn ( Zea mays) in Male Rats.Journal of evidence-based complementary & alternative medicine · 2017Article
- A review on plants used for improvement of sexual performance and virility.BioMed research international · 2014Review
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Authors and funding
4 authors at 2 institutions in 2 countries.
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Abstract
Dracaena arborea is a medicinal plant with ethnopharmacological aphrodisiac reputation. In the present study, the effect of an intravenous administration of aqueous and ethanolic extracts from the dried roots of this plant on the ejaculatory pattern of spinal cord-transected and urethane-anaesthetized rats was investigated. In addition, the effects of these extracts were also determined on dopamine and oxytocin-induced ejaculation. Systemic administration of aqueous and ethanolic extracts (5, 20, 60, 100 mg kg(-1)) of D. arborea did not activate fictive ejaculation, whereas dopamine (0.1 μM kg(-1)) and oxytocin (0.5 UI kg(-1)) provoked ejaculation evidenced by the rhythmic contractions of the bulbospongiosus muscles accompanied with penile erection and sometimes with expulsion of the seminal plugs. Pretreatment of spinal rats with D. arborea extracts dose-dependently blocked the pro-ejaculatory activity of dopamine and oxytocin. In conclusion, the present study shows that the bioactive substances present in the extracts of D. arborea inhibit the activity of the bulbospongiosus muscles through the blockade of dopaminergic and oxytocinergic receptors in rats.
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