ArticleJournal of magnetic resonance imaging : JMRI2014
Measuring venous blood oxygenation in fetal brain using susceptibility-weighted imaging.
Article in Journal of magnetic resonance imaging : JMRI, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 35 citations in OpenAlex.
- Advancements in MRI application in the morphological development of fetal cerebral venous system: a review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025Review
- Recent Advances in MR Imaging-based Quantification of Brain Oxygen Metabolism.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2024Review
- QSM Throughout the Body.Journal of magnetic resonance imaging : JMRI · 2023Review
- Magnetic resonance imaging of the monkey fetal brain in utero.Investigative magnetic resonance imaging · 2022Article
- Quantitative Distribution of Cerebral Venous Oxygen Saturation and Its Prognostic Value in Patients with Acute Ischemic Stroke.Brain sciences · 2022Article
- Cerebral oxygen extraction fraction MRI: Techniques and applications.Magnetic resonance in medicine · 2022Review
- Value of pre- and postnatal magnetic resonance imaging in the evaluation of congenital central nervous system anomalies.Pediatric radiology · 2022Review
- Quantitative Susceptibility Mapping of Venous Vessels in Neonates with Perinatal Asphyxia.AJNR. American journal of neuroradiology · 2021Article
- The application ofJournal of developmental origins of health and disease · 2021Review
- Feasibility of QSM in the human placenta.Magnetic resonance in medicine · 2021Article
- Development of Brain Networks In Utero: Relevance for Common Neural Disorders.Biological psychiatry · 2020Review
- Dual-Imaging Modality Approach to Evaluate Cerebral Hemodynamics in Growth-Restricted Fetuses: Oxygenation and Perfusion.Fetal diagnosis and therapy · 2020Article
- Quantitative susceptibility mapping in the human fetus to measure blood oxygenation in the superior sagittal sinus.European radiology · 2019Article
- Imaging putative foetal cerebral blood oxygenation using susceptibility weighted imaging (SWI).European radiology · 2018Article
- Fetal neuroimaging: an update on technical advances and clinical findings.Pediatric radiology · 2018Review
- Reduced deep regional cerebral venous oxygen saturation in hemodialysis patients using quantitative susceptibility mapping.Metabolic brain disease · 2018Article
- Susceptibility-based time-resolved whole-organ and regional tissue oximetry.NMR in biomedicine · 2017Review
- Susceptibility-weighted imaging: current status and future directions.NMR in biomedicine · 2017Review
- Magnetic resonance angiography of fetal vasculature at 3.0 T.European radiology · 2016Article
- Longitudinal Changes in Placental Magnetic Resonance Imaging Relaxation Parameter in Murine Pregnancy: Compartmental Analysis.Gynecologic and obstetric investigation · 2016Article
Corrections and comments
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Authors and funding
12 authors at 4 institutions in 2 countries.
Funding
Abstract
purposeTo evaluate fetal cerebral venous blood oxygenation, Yv, using principles of MR susceptometry. MATERIALS AND
methodsA cohort of 19 pregnant subjects, with a mean gestational age of 31.6 ± 4.7 weeks were imaged using a modified susceptibility-weighted imaging (SWI) sequence. Data quality was first assessed for feasibility of oxygen saturation measurement, and data from five subjects (mean ± std gestational age of 33.7 ± 3.6 weeks) were then chosen for further quantitative analysis. SWI phase in the superior sagittal sinus was used to evaluate oxygen saturation using the principles of MR susceptometry. Systematic error in the measured Y(v) values was studied through simulations.
resultsSimulations showed that the systematic error in Yv depended upon the assumed angle of the vessel, θ, relative to the main magnetic field and the error in that vessel angle δθ. For the typical vessel angle of θ = 30° encountered in the fetal data analyzed, a δθ as large as ±20° led to an absolute error, δYv, of less than 11%. The measured mean oxygen saturation across the five fetuses was 66% ± 9.4%. This average cerebral venous blood oxygenation value is in close agreement with values in the published literature.
conclusionWe have reported the first in vivo measurement of human fetal cerebral venous oxygen saturation using MRI.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.