ArticleJournal of clinical and diagnostic research : JCDR2014
Effect of various physical stress models on serum cortisol level in wistar rats.
Article in Journal of clinical and diagnostic research : JCDR, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
21 citing papers in PubMed, 37 citations in OpenAlex.
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- Corticosterone effects induced by stress and immunity and inflammation: mechanisms of communication.Frontiers in endocrinology · 2025Review
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- Dopamine Gene Polymorphism, Biochemical and Oxidative Stress Parameters in Geriatric Population with and Without Depression: A Pilot Study.Indian journal of clinical biochemistry : IJCB · 2022Article
- The Preventive Role ofJournal of veterinary research · 2021Article
- The Effect of Aerobic Physical Activity in Adrenaline Level in White Laboratory Rats.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2020Article
- Prostate cancer cell growth characteristics in serum and prostate-conditioned media from moderate-intensity exercise-trained healthy and tumor-bearing rats.American journal of cancer research · 2019Article
- Effects of Pulsed Electromagnetic Field with Predatory Stress on Functional and Histological Index of Injured-Sciatic Nerve in Rat.Bulletin of emergency and trauma · 2017Article
- The role of neuropeptide-Y in nandrolone decanoate-induced attenuation of antidepressant effect of exercise.PloS one · 2017Article
- Osho Dynamic Meditation's Effect on Serum Cortisol Level.Journal of clinical and diagnostic research : JCDR · 2016Article
- Effects of voluntary exercise on apoptosis and cortisol after chronic restraint stress in mice.Journal of exercise nutrition & biochemistry · 2016Article
- Effect of Drug Alprazolam on Restrained Stress Induced Alteration of Serum Cortisol and Antioxidant Vitamins (Vitamin C and E) in Male Albino Rats.Journal of clinical and diagnostic research : JCDR · 2016Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStress indicates the response or reaction of an organism to the environmental circumstances and their outcomes. Acute stress is well known to trigger several hormonal alterations in animals. An increase in glucocorticoid concentration can represent intensity of discomfort or distress experienced by an animal. The study was undertaken to evaluate the effects of various physical stress models on serum cortisol level in Wistar male rats. METHODOLOGY: In this study six Wistar male rats weighing 150-200 gm were randomly selected. Animals were exposed to 'forced swim test' and 'restraint test'. Their serum cortisol level was measured by ELISA test using alpha prime ELISA system before and after the tests respectively.
resultsRESULTS were analyzed by students paired t-test. Serum cortisol level was significantly higher after forced swim test as well as after restraint test. When both the physical activities were compared, serum cortisol level was increased more after restraint stress than after forced swim test however, the difference was not significant statistically. INTERPRETATION AND
conclusionThe rise in serum cortisol level was observed in both the physical activity models . Rise in serum cortisol level was significantly higher after restraint test than exposing them to forced swim test. This indicates that restraining the rats produced more stress than making them forcefully swim.
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