Evidence map›Paper›PMID 24783074›Full record

ArticleJournal of clinical and diagnostic research : JCDR2014

Antidepressant activity of brahmi in albino mice.

Sldv Ramana Murty Kadali, Das M C, Srinivasa Rao A S R, Karuna Sri G

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical and diagnostic research : JCDR, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Ethnomedicinal Use, Phytochemistry, and Pharmacology ofEvidence-based complementary and alternative medicine : eCAM · 2021
    Review
  3. Vasodilatory Effects and Mechanisms of Action ofMolecules (Basel, Switzerland) · 2019
    Article
  4. Ayurveda management of Major Depressive Disorder: A case study.Journal of Ayurveda and integrative medicine
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sldv Ramana Murty KadaliTutor, Department of Pharmacology, NRI Medical College , A.P, India .
Das M CProfessor and HOD, Department of Pharmacology, NRI Medical College , A.P, India .
Srinivasa Rao A S RAssosiate Professor, Department of Pharmacology, NRI Medical College , A.P, India .
Karuna Sri GTutor, Department of Pharmacology, NRI Medical College , A.P, India .
Sarojini Naidu Medical College · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextIn traditional system of medicine brahmi has been used to enhance memory. Recently it has been reported to have action in psychiatric disorders. With these backgrounds the work has been undertaken to study antidepressant activity of brahmi in albino mice.

aimTo evaluate antidepressant activity of brahmi in experimental models. MATERIALS AND

methodsThe antidepressant activity was studied in albino mice using forced swimming test (FST), tail suspension test (TST) and shock induced depression (SID). Imipramine (10mg/kg), fluoxetine (30mg/kg) were used as standard drugs and brahmi (10, 20, 30mg/kg) was used as test drug.

resultsBrahmi exhibited significant decrease in duration of immobility in FST and reduced the shock induced decrease in activity in SID models. It didn't show any activity in the TST model.

conclusionBrahmi has shown antidepressant activity in FST and SID.

Indexed as

Antidepressant activityBrahmiForced swim testTail suspension test

Identifiers

PMID24783074
PMCPMC4003678
OpenAlexW2077819967

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.