Evidence map›Paper›PMID 24783044›Full record

ArticleEuropean thyroid journal2013

2013 European thyroid association guidelines for the diagnosis and treatment of thyrotropin-secreting pituitary tumors.

P Beck-Peccoz, A Lania, A Beckers, K Chatterjee, J-L Wemeau

Open access · bronzeAbstract read
In one paragraph

Article in European thyroid journal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 111 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
111citing papers in PubMed, 3 pooled it
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

111 citing papers in PubMed, 3 syntheses or guidelines pooled it, 278 citations in OpenAlex.

  1. Guideline
  2. Guideline
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. The clinical value of [Pituitary · 2026
    Observational
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. Article
  19. A subtle initial clinical presentation of a TSH-secreting PitNET.Endocrinology, diabetes & metabolism case reports · 2025
    Article
  20. Observational

51 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

P Beck-PeccozDepartment of Clinical Sciences and Community Health, University of Milan, Endocinology and Diabetology Unit, Fondazione IRCCS Cà Granda Policlinico, Milan, Italy.
A LaniaDipartimento di Biotecnologie Mediche e Medicina Traslazionale, University of Milan, Endocrine Unit, Istituto Clinico Humanitas IRCCS, Rozzano, Milan, Italy.
A BeckersService d'Endocrinologie, Centre Hospitalier Universitaire de Liège, Université de Liège, Liège, Belgium.
K ChatterjeeInstitute of Metabolic Science, Metabolic Research Laboratories, Addenbrooke's Hospital, University of Cambridge, Cambridge, UK.
J-L WemeauCHRU, Hôpital Claude-Huriez, Clinique Endocrinologique Marc-Linquette, Lille, France.
Addenbrooke's Hospital · GB

Funding

Wellcome Trust 095564
6 · The paper itself

Abstract

Hyperthyroidism is mainly due to autoimmune thyroid disorders or toxic goiter, and very rarely to the presence of thyrotropin (TSH)-secreting pituitary adenomas (TSHomas). These tumors are characterized by high levels of circulating free thyroid hormones (FT4 and FT3) in the presence of nonsuppressed serum TSH concentrations. Failure to correctly diagnose TSHomas may result in inappropriate thyroid ablation, which results in a significant increase of pituitary tumor mass. The diagnosis is mainly achieved by measuring TSH after T3 suppression and TRH stimulation tests. These dynamic tests, together with pituitary imaging and genetic testing are useful in distinguishing TSHomas from the syndromes of resistance to thyroid hormone action. The treatment of choice is surgery. In cases of surgical failure, somatostatin analogs have been found to be effective in normalizing TSH secretion in more than 90% of patients.

Indexed as

Central hyperthyroidismResistance to thyroid hormonesSomatostatin analogsThyrotropinThyrotropin-secreting pituitary adenomaTranssphenoidal surgery

Identifiers

PMID24783044
PMCPMC3821512
OpenAlexW2047837716

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.