ArticleFrontiers in neuroscience2014
The EEG as an index of neuromodulator balance in memory and mental illness.
Article in Frontiers in neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- EEG Time-Frequency Clustering Reveals Spectral Signatures of Glutamatergic and Cholinergic Activities and Their Interrelations.Biomedicines · 2026Article
- State-Dependent CNN-GRU Reinforcement Framework for Robust EEG-Based Sleep Stage Classification.Biomimetics (Basel, Switzerland) · 2026Article
- Clustering Cortical Rhythms: Monoaminergic Signatures in Time-Frequency EEG Dynamics.Biomedicines · 2025Article
- High-definition transcranial direct current stimulation of the parietal cortices modulates the neural dynamics underlying verbal working memory.Human brain mapping · 2024Article
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- Acute effects of 2.856 GHz and 1.5 GHz microwaves on spatial memory abilities and CREB-related pathways.Scientific reports · 2021Article
- DelIrium VULnerability in GEriatrics (DIVULGE) study: a protocol for a prospective observational study of electroencephalogram associations with incident postoperative delirium.BMJ neurology open · 2021Article
- Heritability of alpha and sensorimotor network changes in temporal lobe epilepsy.Annals of clinical and translational neurology · 2020Article
- Hyper-Activation of mPFC Underlies Specific Traumatic Stress-Induced Sleep-Wake EEG Disturbances.Frontiers in neuroscience · 2020Article
- Remembering to Forget: A Dual Role for Sleep Oscillations in Memory Consolidation and Forgetting.Frontiers in cellular neuroscience · 2019Article
- Grand Total EEG Score Can Differentiate Parkinson's Disease From Parkinson-Related Disorders.Frontiers in neurology · 2019Article
- Pregnane X Receptor Deletion Modifies Recognition Memory and Electroencephalographic Activity.Neuroscience · 2018Article
- Recent advances in the effects of microwave radiation on brains.Military Medical Research · 2017Review
- Scopolamine Reduces Electrophysiological Indices of Distractor Suppression: Evidence from a Contingent Capture Task.Frontiers in neural circuits · 2017Article
- Transcranial low-level infrared laser irradiation ameliorates depression induced by reserpine in rats.Lasers in medical science · 2016Article
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Abstract
There is a strong correlation between signature EEG frequency patterns and the relative levels of distinct neuromodulators. These associations become particularly evident during the sleep-wake cycle. The monoamine-acetylcholine balance hypothesis is a theory of neurophysiological markers of the EEG and a detailed description of the findings that support this proposal are presented in this paper. According to this model alpha rhythm reflects the relative predominance of cholinergic muscarinic signals and delta rhythm that of monoaminergic receptor effects. Both high voltage synchronized rhythms are likely mediated by inhibitory Gαi/o-mediated transduction of inhibitory interneurons. Cognitively, alpha and delta EEG measures are proposed to indicate automatic and flexible strategies, respectively. Sleep is associated with marked changes in relative neuromodulator levels corresponding to EEG markers of distinct stages. Sleep studies on memory consolidation present some of the strongest evidence yet for the respective roles of monoaminergic and cholinergic projections in declarative and non-declarative memory processes, a key theoretical premise for understanding the data. Affective dysregulation is reflected in altered EEG patterns during sleep.
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