ArticleInternational journal of obesity (2005)2014
Prevalence of functional gastrointestinal disorders in obese and overweight children.
Article in International journal of obesity (2005), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 3 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Global Prevalence of Functional Abdominal Pain Disorder among Children and Adolescents According to the Rome III and IV Criteria: A Systematic Review and Meta-Analysis.Gut and liver · 2026Pooled it
- The relationship between functional constipation and overweight/obesity in children: a systematic review and meta-analysis.Pediatric research · 2023Pooled it
- Guidelines for treating child and adolescent obesity: A systematic review.Frontiers in nutrition · 2022Pooled it
- Eating behaviors and quality of life in preadolescents at risk for obesity with and without abdominal pain.Journal of pediatric gastroenterology and nutrition · 2015Trial
- Body mass index and gastrointestinal inflammation: Bio-molecular pathophysiology.World journal of gastrointestinal pathophysiology · 2026Review
- Clinical characteristics and nutritional profiles of children with different irritable bowel syndrome subtypes: a retrospective hospital-based study.Translational pediatrics · 2026Article
- Review
- Effects of body mass index on gastric motility: Comparing children with functional abdominal pain disorders and healthy controls.World journal of clinical pediatrics · 2025Article
- Spectrum of Functional Abdominal Pain Disorders in Children and Their Clinical, Social Characteristics: A Cross-Sectional Study.JGH open : an open access journal of gastroenterology and hepatology · 2025Article
- Night shift work increases the risk of developing irritable bowel syndrome: a prospective cohort study in the UK Biobank.Frontiers in public health · 2025Article
- Functional Gastrointestinal Disorders and Childhood Obesity: The Role of Diet and Its Impact on Microbiota.Nutrients · 2024Review
- A causal association between obesity and constipation: a two-sample bidirectional Mendelian randomization study and meta-analysis.Frontiers in nutrition · 2024Review
- Functional Gastrointestinal Disorders and Abdominal Visceral Fat in Children and Adolescents.Pediatric gastroenterology, hepatology & nutrition · 2023Article
- Assesment of functional gastrointestinal diseases in obese children.European journal of pediatrics · 2023Article
- Influence of Body Mass Index on the Evaluation and Management of Pediatric Abdominal Pain in the Emergency Department.The western journal of emergency medicine · 2023Article
- Mental health in children and adolescents with overweight or obesity.BMC public health · 2023Article
- Nutritional Status and Selected Adipokines in Children with Irritable Bowel Syndrome.Nutrients · 2022Article
- Association of Gastric Myoelectrical Activity With Ghrelin, Gastrin, and Irisin in Adults With Metabolically Healthy and Unhealthy Obesity.Frontiers in physiology · 2022Article
- Systematic Review of Pediatric Functional Gastrointestinal Disorders (Rome IV Criteria).Journal of clinical medicine · 2021Review
- Lifestyle, psychological stress, and incidence of adolescent constipation: results from the Toyama birth cohort study.BMC public health · 2021Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
objectiveTo compare the prevalence of functional gastrointestinal disorders such as functional constipation (FC), functional abdominal pain (FAP), functional abdominal pain syndrome (FAPS) and irritable bowel syndrome (IBS) between a large cohort of healthy obese/overweight children and normal-weight children.
methodsHealthy children between the ages of 4 and 18 years were eligible for recruitment from the Yale Pediatric Primary Care clinic, Yale Adolescent clinic and a local private practice in Orange, CT, USA. Study subjects or their parents were interviewed using a questionnaire based on the ROME III standardized criteria for diagnosing functional gastrointestinal disorders. Medical records were reviewed to collect information about age, gender, height, weight, body mass index (BMI), ethnicity and chronic medical conditions. Children were classified into obese, overweight and normal-weight based on their BMI for age and gender. Data were analyzed to compare the prevalence of FC, FAP, FAPS and IBS between obese/overweight children and normal-weight children.
resultsA total of 450 children (45% males) were recruited. There were 191 (42%) obese/overweight children and 259 (58%) normal-weight children. FAPS (odds ratio (OR) =2.1, 95% confidence interval (CI): 1.21-3.64, P=0.007), FC (OR=1.83, 95% CI: 1.12-2.98, P=0.01), and IBS (OR=2.59, 95% CI: 1.40-4.79, P=0.003) were significantly more prevalent in the obese/overweight children than in the normal-weight children. Of the obese/overweight children, 47% had at least one functional gastrointestinal disorder compared with 27% of the normal-weight children (P⩽0.001). Only 36% of the children with functional gastrointestinal disorders sought medical attention for their symptoms.
conclusionsObese/overweight children have a higher prevalence of functional gastrointestinal disorders than normal-weight children. Almost half of the obese/overweight children had at least one functional gastrointestinal disorder.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.