Evidence map›Paper›PMID 24781600›Full record

ArticleSurgery today2015

Preoperative plasma D-dimer level is an independent prognostic factor in patients with completely resected non-small cell lung cancer.

Koichi Fukumoto, Tetsuo Taniguchi, Noriyasu Usami, Koji Kawaguchi, Takayuki Fukui, Futoshi Ishiguro, Shota Nakamura, Kohei Yokoi

Abstract read
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Article in Surgery today, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  16. [Correlation between Plasma D-dimer Count and Features of
Non-small Cell Lung Cancer].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Koichi FukumotoDepartment of Thoracic Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.
Tetsuo Taniguchi
Noriyasu Usami
Koji Kawaguchi
Takayuki Fukui
Futoshi Ishiguro
Shota Nakamura
Kohei Yokoi

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe plasma D-dimer (D-dimer) level, a marker of hypercoagulation, has been reported to be associated with survival in several types of cancers. This retrospective study was conducted to evaluate the prognostic significance of the preoperative D-dimer level in patients with completely resected non-small cell lung cancer (NSCLC).

methodsA total of 237 completely resected NSCLC patients were included in this study. In addition to age, sex, the smoking status, etc., the association between the preoperative D-dimer level and survival was explored.

resultsThe patients were divided into three groups according to the D-dimer level: group A (≤ 0.50 μg/ml, n = 76), group B (0.51-0.86 μg/ml, n = 79) and group C (>0.86 μg/ml, n = 82). The 5-year overall survival rate was 89.6 % (95 % confidence interval (CI) 77.7-95.3) for group A, 75.1 % (95 % CI 62.3-83.6) for group B and 60.1 % (95 % CI 46.8-71.1) for group C (P trend <0.001). A multivariate survival analysis showed that the D-dimer level (group B vs. group A HR 4.25, group C vs. group A HR 4.11) was an independent significant prognostic factor, in addition to age, sex, the pathological stage and the serum carcinoembryonic antigen level.

conclusionsThe preoperative D-dimer level is an independent prognostic factor in patients with completely resected NSCLC.

Indexed as

Preoperative PeriodAdultAgedAged, 80 and overBiomarkers, TumorCarcinoembryonic AntigenCarcinoma, Non-Small-Cell LungFemaleFibrin Fibrinogen Degradation ProductsForecastingHumansLung NeoplasmsMaleMiddle AgedNeoplasm StagingPneumonectomyBiomarkers, TumorCarcinoembryonic AntigenFibrin Fibrinogen Degradation Productsfibrin fragment D

Identifiers

PMID24781600

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.