ArticleNature methods2014
A synthetic approach to abiogenesis.
Article in Nature methods, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Thresholds in Origin of Life Scenarios.iScience · 2020Review
- An RNA polymerase ribozyme that synthesizes its own ancestor.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Self-replication of DNA by its encoded proteins in liposome-based synthetic cells.Nature communications · 2018Article
- Prebiotic Factors Influencing the Activity of a Ligase Ribozyme.Life (Basel, Switzerland) · 2017Article
- Simple peptides derived from the ribosomal core potentiate RNA polymerase ribozyme function.Nature chemistry · 2017Article
- Combinatorial selection for replicable RNA by Qβ replicase while maintaining encoded gene function.PloS one · 2017Article
- Amplification of RNA by an RNA polymerase ribozyme.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- DNA nanotechnology: new adventures for an old warhorse.Current opinion in chemical biology · 2015Review
- Generation of Aptamers with an Expanded Chemical Repertoire.Molecules (Basel, Switzerland) · 2015Review
- Synthetic Biology: A Bridge between Artificial and Natural Cells.Life (Basel, Switzerland) · 2014Review
- Reconciling ligase ribozyme activity with Fatty Acid vesicle stability.Life (Basel, Switzerland) · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Synthetic biology seeks to probe fundamental aspects of biological form and function by construction (resynthesis) rather than deconstruction (analysis). Here we discuss how such an approach could be applied to assemble synthetic quasibiological systems able to replicate and evolve, illuminating universal properties of life and the search for its origins.
Indexed as
Identifiers
24781322What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.