Evidence map›Paper›PMID 24780180›Full record

Trial reportJournal of pain and symptom management2014

Mindfulness-oriented recovery enhancement ameliorates the impact of pain on self-reported psychological and physical function among opioid-using chronic pain patients.

Eric L Garland, Elizabeth Thomas, Matthew O Howard

Open access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of pain and symptom management, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 3 pooled it
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 39 citations in OpenAlex.

  1. Pooled it
  2. A Systematic Review of the Adherence to Home-Practice Meditation Exercises in Patients with Chronic Pain.International journal of environmental research and public health · 2023
    Pooled it
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  16. Mindfulness Meditation and Psychopathology.Annual review of clinical psychology · 2019
    Review
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  19. Abuse of Opioid Analgesics Is Missing.Deutsches Arzteblatt international · 2016
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Eric L GarlandHuntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA; College of Social Work, University of Utah, Salt Lake City, Utah, USA. Electronic address: elgarlan@gmail.com.
Elizabeth ThomasCollege of Social Work, University of Utah, Salt Lake City, Utah, USA.
Matthew O HowardSchool of Social Work, University of North Carolina, Chapel Hill, North Carolina, USA.
University of Utah · USUniversity of North Carolina at Chapel Hill · US

Funding

Targeting Military Opioid Misuse with Mindfulness-Oriented Recovery EnhancementR34DA037005 · NIDA · UNIVERSITY OF UTAH · PI GARLAND, ERIC LEE · 2013 to 2015
$667k
Mindfulness-Oriented Recovery Enhancement For Chronic Pain Patients Receiving OpiR03DA032517 · NIDA · FLORIDA STATE UNIVERSITY · PI GARLAND, ERIC LEE · 2011 to 2012
$74k
NIDA NIH HHS DA032517NIDA NIH HHS DA037005NIDA NIH HHS R03 DA032517NIDA NIH HHS R34 DA037005
6 · The paper itself

Abstract

contextChronic pain impacts one-third of the U.S. population, and its effects are debilitating for individuals and costly to the medical system. Although opioids are commonly prescribed to address chronic pain, they confer risk for misuse and addiction in some patients and may not fully restore life function-particularly with regard to psychosocial factors. Because of the multiplicity of impacts that chronic pain may have on daily functioning, broad-spectrum behavioral interventions are needed.

objectivesThe purpose of this study was to conduct follow-up analyses from a pilot randomized controlled trial of Mindfulness-Oriented Recovery Enhancement (MORE) to assess specific effects of MORE on various biopsychosocial aspects of pain-related impairment.

methodsChronic pain patients (N = 115; mean age, 48 ± 14 years; 68% female) were randomly assigned to either eight weeks of MORE or a support group. Domains of pain-related functional interference were measured with the Brief Pain Inventory at pre- and post-treatment and at a three-month follow-up. Treatment effects were analyzed with multivariate intention-to-treat models.

resultsMORE participants reported significantly greater reductions in functional interference than support group participants at post-treatment across all domains, including general activity, mood, walking ability, normal work, relationships, sleep, and enjoyment of life. These effects were largely maintained by the three-month follow-up; however, general activity level and walking ability were no longer significant, indicating differential long-term effects between physiological and psychological functioning.

conclusionFindings demonstrate preliminary efficacy of MORE as a treatment for pain-related functional impairments and suggest that effects may be more pronounced and durable for aspects of psychological function.

Indexed as

Analgesics, OpioidChronic PainFemaleFollow-Up StudiesHumansMaleMiddle AgedMindfulnessMultivariate AnalysisPain MeasurementPilot ProjectsQuality of LifeSelf ReportTreatment OutcomeAnalgesics, Opioidchronic painfunctionimpairmentMindfulnessopioidquality of life

Identifiers

PMID24780180
PMCPMC4209314
OpenAlexW2042849005

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.