ArticleJournal of clinical hypertension (Greenwich, Conn.)2014
Effects of moderate aerobic exercise training on vascular health and blood pressure in African Americans.
Article in Journal of clinical hypertension (Greenwich, Conn.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Effects of Different Types of Exercise Training on Endothelial Function in Prehypertensive and Hypertensive Individuals: A Systematic Review.Arquivos brasileiros de cardiologia · 2021Pooled it
- Individuals with controlled hypertension show endothelial integrity following a bout of moderate-intensity exercise: randomized clinical trial.Scientific reports · 2021Trial
- Respiratory muscle training positively affects vasomotor response in young healthy women.PloS one · 2018Trial
- Effects of 24-Week Aerobic and Resistance Training on Carotid Artery Intima-Media Thickness and Flow Velocity in Elderly Women with Sarcopenic Obesity.Journal of atherosclerosis and thrombosis · 2017Trial
- Effects of 8-Week Hatha Yoga Training on Metabolic and Inflammatory Markers in Healthy, Female Chinese Subjects: A Randomized Clinical Trial.BioMed research international · 2016Trial
- The effect of physical activity on cardiometabolic health and inflammation in treated HIV infection.Antiviral therapy · 2016Trial
- Influence of Sedentary Behaviour Interventions on Vascular Functions and Cognitive Functions in Hypertensive Adults-A Scoping Review on Potential Mechanisms and Recommendations.International journal of environmental research and public health · 2022Article
- Tactical Circuit Training Improves Blood Pressure and Vascular Health More Than Resistance Training.International journal of exercise science · 2021Article
- Vascular Endothelial Function in Midlife/Older Adults Classified According to 2017 American College of Cardiology/American Heart Association Blood Pressure Guidelines.Journal of the American Heart Association · 2020Article
- An Overview of the Cardiorespiratory Hypothesis and Its Potential Contribution to the Care of Neurodegenerative Disease in Africa.Medicina (Kaunas, Lithuania) · 2019Review
- Exercise-Derived Microvesicles: A Review of the Literature.Sports medicine (Auckland, N.Z.) · 2018Review
- Effects of circuit exercise training on vascular health and blood pressure.Preventive medicine reports · 2018Article
- Article
- Systemic FDiversity and equality in health and care · 2017Article
- Vascular Health in American Football Players: Cardiovascular Risk Increased in Division III Players.International journal of vascular medicine · 2016Article
- Causes of changes in carotid intima-media thickness: a literature review.Cardiovascular ultrasound · 2015Review
- Effect of Interleukin-10 and Laminar Shear Stress on Endothelial Nitric Oxide Synthase and Nitric Oxide in African American Human Umbilical Vein Endothelial Cells.Ethnicity & disease · 2015Article
- Article
- Carotid Artery IMT, Blood Pressure, and Cardiovascular Risk Factors in Males and Females.International journal of exercise scienceArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors at 7 institutions in 1 country.
Funding
Abstract
As healthcare progresses toward individualized medicine, understanding how different racial groups respond to lifestyle interventions is valuable. It is established that African Americans have disproportionate levels of cardiovascular disease and impaired vascular health, and clinical practice guidelines suggest lifestyle interventions as the first line of treatment. Recently, the authors reported that 6 months of aerobic exercise improved inflammatory markers, flow-mediated dilation (FMD), and levels of circulating endothelial microparticles (EMPs) in African American adults. This study is a subgroup analysis of the aerobic exercise-induced changes in vascular health and blood pressure (BP) measures, including carotid artery intima-media thickness (IMT), nitroglycerin-mediated dilation (NMD), ambulatory BP, and office BP. Sedentary African American adults (53.4±6.2 years; 21 women and 5 men) showed improved vascular health but no change in BP. Carotid artery IMT decreased 6.4%, plasma nitric oxide levels increased 76.6%, plasma EMP levels decreased, percentage of FMD increased 59.6%, and FMD/NMD ratio increased 36.2% (P<.05 for all). Six months of aerobic exercise training is sufficient to elicit improvements in vascular structure and function in African Americans, even without improvements in BP measures or NMD (ie, smooth muscle function). To our knowledge, this is the first study to report such findings in African Americans.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.