Evidence map›Paper›PMID 24779654›Full record

ArticleBiometrics2014

Estimating peer effects in longitudinal dyadic data using instrumental variables.

A James O'Malley, Felix Elwert, J Niels Rosenquist, Alan M Zaslavsky, Nicholas A Christakis

Open access · hybridAbstract read
In one paragraph

Article in Biometrics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Identification and estimation of causal peer effects using double negative controls for unmeasured network confounding.Journal of the Royal Statistical Society. Series B, Statistical methodology · 2024
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  13. Review
  14. The Use of Instrumental Variables in Peer Effects Models.Oxford bulletin of economics and statistics · 2019
    Article
  15. Article
  16. The social genome of friends and schoolmates in the National Longitudinal Study of Adolescent to Adult Health.Proceedings of the National Academy of Sciences of the United States of America · 2018
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 1 country.

A James O'MalleyThe Dartmouth Institute for Health Policy and Clinical Practice, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire 03766, U.S.A.
Felix ElwertDepartment of Sociology, Center for Demography and Ecology, University of Wisconsin-Madison, Madison, Wisconsin 53706, U.S.A.
J Niels RosenquistDepartment of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts 02114, U.S.A.
Alan M ZaslavskyDepartment of Health Care Policy, Harvard Medical School, Boston, Massachusetts 02115, U.S.A.
Nicholas A ChristakisDepartment of Sociology, Yale Institute for Network Science, Yale University, New Haven, Connecticut 06520, U.S.A.
Dartmouth Institute for Health Policy and Clinical Practice · USHarvard University · USMassachusetts General Hospital · USUniversity of Wisconsin–Madison · USYale University · US

Funding

Statistical Data Enclave CoreP30AG017266 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI Michal Engelman · 1999 to 2026
$17.0M
The Spread of Health Behaviors in the Framingham Heart Study Social NetworkP01AG031093 · NIA · YALE UNIVERSITY · PI MCGUIRE, THOMAS G. · 2008 to 2012
$10.7M
Scientific and Technical CoreP2CHD047873 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI Katherine J. Curtis · 2014 to 2026
$5.1M
Social Network Study of Health Effects in AgingR01AG024448 · NIA · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI CHRISTAKIS, NICHOLAS A · 2004 to 2006
$2.0M
SLEEP AND ENTRAINMENT OF SCN FUNCTIONR01HL064278 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI STROHL, KINGMAN PERKINS · 1999 to 2002
$871k
THE FRAMINGHAM HEART STUDY-N01HC25195-268025195-268025195N01HC025195 · HC · TRUSTEES OF BOSTON UNIVERSITY · PI WOLF, PHILIP A · 2002 to 2006
–
NHLBI NIH HHS N01 HC025195NHLBI NIH HHS N01-HC-25195NHLBI NIH HHS N02 HL064278NIA NIH HHS P01 AG031093NIA NIH HHS P30 AG017266NIA NIH HHS R01 AG024448NICHD NIH HHS P2C HD047873
6 · The paper itself

Abstract

The identification of causal peer effects (also known as social contagion or induction) from observational data in social networks is challenged by two distinct sources of bias: latent homophily and unobserved confounding. In this paper, we investigate how causal peer effects of traits and behaviors can be identified using genes (or other structurally isomorphic variables) as instrumental variables (IV) in a large set of data generating models with homophily and confounding. We use directed acyclic graphs to represent these models and employ multiple IV strategies and report three main identification results. First, using a single fixed gene (or allele) as an IV will generally fail to identify peer effects if the gene affects past values of the treatment. Second, multiple fixed genes/alleles, or, more promisingly, time-varying gene expression, can identify peer effects if we instrument exclusion violations as well as the focal treatment. Third, we show that IV identification of peer effects remains possible even under multiple complications often regarded as lethal for IV identification of intra-individual effects, such as pleiotropy on observables and unobservables, homophily on past phenotype, past and ongoing homophily on genotype, inter-phenotype peer effects, population stratification, gene expression that is endogenous to past phenotype and past gene expression, and others. We apply our identification results to estimating peer effects of body mass index (BMI) among friends and spouses in the Framingham Heart Study. Results suggest a positive causal peer effect of BMI between friends.

Indexed as

Models, StatisticalSocial NetworkingBiasBody Mass IndexBody SizeComputer SimulationFriendsGenome-Wide Association StudyHumansLongitudinal StudiesObesitySelection BiasBody‐mass indexCausalityDirected acyclic graphsDyadGenesHomophilyInstrumental variableLongitudinalMendelian randomizationPeer effectSocial networkTwo‐stage least squares

Identifiers

PMID24779654
PMCPMC4213357
OpenAlexW2170444996

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.