Evidence map›Paper›PMID 24779521›Full record

ArticleAIDS care2014

Development of an electronic medical record-based algorithm to identify patients with unknown HIV status.

Uriel R Felsen, Eran Y Bellin, Chinazo O Cunningham, Barry S Zingman

Open access · greenAbstract read
In one paragraph

Article in AIDS care, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 40 citations in OpenAlex.

  1. Trial
  2. Development and Evaluation of a Novel Algorithm to Identify Doxycycline Postexposure Prophylaxis Users at a Large Healthcare System in the Bronx, New York.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Article
  3. Article
  4. Automated HIV Case Identification from the MIMIC-IV Database.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2024
    Article
  5. Observational
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  7. Article
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  9. Article
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  13. Article
  14. Article
  15. Article
  16. Adjudicated Heart Failure in HIV-Infected and Uninfected Men and Women.Journal of the American Heart Association · 2018
    Article
  17. Article
  18. Article
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Uriel R Felsena Division of Infectious Diseases , Montefiore Medical Center , Bronx , NY , USA.
Eran Y Bellin
Chinazo O Cunningham
Barry S Zingman
Montefiore Medical Center · US

Funding

Core-010UL1TR001073 · NCATS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI KELLER, MARLA J, SHAMOON, HARRY · 2013 to 2017
$21.3M
CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR025750 · NCRR · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI SHAMOON, HARRY · 2008 to 2011
$20.5M
Immunology/Pathology CoreP30AI051519 · NIAID · YESHIVA UNIVERSITY · PI KLEIN, ROBERT STEPHEN · 2003 to 2013
$18.6M
Abstinence Reinforcing Contingency Management to Suppress HIV Viral LoadR01DA032110 · NIDA · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI CUNNINGHAM, CHINAZO · 2011 to 2015
$3.6M
HIV and Substance Abuse Clinical Addiction Research and Education (CARE) ProgramR25DA023021 · NIDA · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI ARNSTEN, JULIA H. · 2007 to 2014
$2.7M
Clinical and Translational Science Award-K12KL2RR025749 · NCRR · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI SHAMOON, HARRY · 2008 to 2011
$991k
Development of a community-based buprenorphine treatment interventionR34DA031066 · NIDA · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI CUNNINGHAM, CHINAZO · 2011 to 2013
$709k
Clinical and Translational Science Award-T32 (TL1)TL1RR025748 · NCRR · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI SHAMOON, HARRY · 2008 to 2011
$385k
NCATS NIH HHS UL1 TR001073NCRR NIH HHS KL2 RR025749NCRR NIH HHS KL2RR025749NCRR NIH HHS TL1 RR025748NCRR NIH HHS TL1RR025748NCRR NIH HHS UL1 RR025750NCRR NIH HHS UL1RR025750NIAID NIH HHS AI-51519NIAID NIH HHS P30 AI051519NIDA NIH HHS R01 DA032110NIDA NIH HHS R01DA032110NIDA NIH HHS R25 DA023021NIDA NIH HHS R25DA023021NIDA NIH HHS R34 DA031066NIDA NIH HHS R34DA031066
6 · The paper itself

Abstract

Individuals with unknown HIV status are at risk for undiagnosed HIV, but practical and reliable methods for identifying these individuals have not been described. We developed an algorithm to identify patients with unknown HIV status using data from the electronic medical record (EMR) of a large health care system. We developed EMR-based criteria to classify patients as having known status (HIV-positive or HIV-negative) or unknown status and applied these criteria to all patients seen in the affiliated health care system from 2008 to 2012. Performance characteristics of the algorithm for identifying patients with unknown HIV status were calculated by comparing a random sample of the algorithm's results to a reference standard medical record review. The algorithm classifies all patients as having either known or unknown HIV status. Its sensitivity and specificity for identifying patients with unknown status are 99.4% (95% CI: 96.5-100%) and 95.2% (95% CI: 83.8-99.4%), respectively, with positive and negative predictive values of 98.7% (95% CI: 95.5-99.8%) and 97.6% (95% CI: 87.1-99.1%), respectively. Using commonly available data from an EMR, our algorithm has high sensitivity and specificity for identifying patients with unknown HIV status. This algorithm may inform expanded HIV testing strategies aiming to test the untested.

Indexed as

AlgorithmsElectronic Health RecordsHIV InfectionsHIV SeronegativityHIV SeropositivityHumansNew York CityReference StandardsSensitivity and Specificityalgorithmelectronic medical recordexpanded HIV testingHIV/AIDS

Identifiers

PMID24779521
PMCPMC4095997
OpenAlexW2023237394

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.