ArticleFrontiers in physiology2014
Epigenetic features in the oyster Crassostrea gigas suggestive of functionally relevant promoter DNA methylation in invertebrates.
Article in Frontiers in physiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Integration of epigenetics into ecotoxicology: insights and fundamental research needs.Biological reviews of the Cambridge Philosophical Society · 2026Review
- The Effects of Larval Cryopreservation on the Epigenetics of the Pacific OysterInternational journal of molecular sciences · 2023Article
- High temperature influences DNA methylation and transcriptional profiles in sea urchins (Strongylocentrotus intermedius).BMC genomics · 2023Article
- Epigenetic and Genetic Population Structure is Coupled in a Marine Invertebrate.Genome biology and evolution · 2023Article
- Cadmium nitrate and DNA methylation in gastropods: comparison between ovotestis and hepatopancreas.PeerJ · 2023Article
- Genome-Wide Differential DNA Methylomes Provide Insights into the Infertility of Triploid Oysters.Marine biotechnology (New York, N.Y.) · 2022Article
- The methylome of Biomphalaria glabrata and other mollusks: enduring modification of epigenetic landscape and phenotypic traits by a new DNA methylation inhibitor.Epigenetics & chromatin · 2021Article
- Sequence determinants, function, and evolution of CpG islands.Biochemical Society transactions · 2021Review
- Comparative Epigenomics Reveals Host Diversity of theFrontiers in cell and developmental biology · 2021Article
- Population epigenetic divergence exceeds genetic divergence in the Eastern oysterEvolutionary applications · 2020Article
- Article
- Elevated temperature attenuates ovarian functions and induces apoptosis and oxidative stress in the American oyster, Crassostrea virginica: potential mechanisms and signaling pathways.Cell stress & chaperones · 2019Article
- What drives phenotypic divergence among coral clonemates of Acropora palmata?Molecular ecology · 2019Article
- DNA methylation in adults and during development of the self-fertilizing mangrove rivulus,Ecology and evolution · 2018Article
- Methylation profile of a satellite DNA constituting the intercalary G+C-rich heterochromatin of the cut trough shell Spisula subtruncata (Bivalvia, Mactridae).Scientific reports · 2017Article
- Dynamics of DNA methylomes underlie oyster development.PLoS genetics · 2017Article
- Aquaculture genomics, genetics and breeding in the United States: current status, challenges, and priorities for future research.BMC genomics · 2017Review
- Molecular and Biochemical Methods Useful for the Epigenetic Characterization of Chromatin-Associated Proteins in Bivalve Molluscs.Frontiers in physiology · 2017Article
- Epigenetic DNA Methylation MediatingFrontiers in physiology · 2017Article
- Inheritance and Variation of Genomic DNA Methylation in Diploid and Triploid Pacific Oyster (Crassostrea gigas).Marine biotechnology (New York, N.Y.) · 2016Article
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Abstract
DNA methylation is evolutionarily conserved. Vertebrates exhibit high, widespread DNA methylation whereas invertebrate genomes are less methylated, predominantly within gene bodies. DNA methylation in invertebrates is associated with transcription level, alternative splicing, and genome evolution, but functional outcomes of DNA methylation remain poorly described in lophotrochozoans. Recent genome-wide approaches improve understanding in distant taxa such as molluscs, where the phylogenetic position, and life traits of Crassostrea gigas make this bivalve an ideal model to study the physiological and evolutionary implications of DNA methylation. We review the literature about DNA methylation in invertebrates and focus on DNA methylation features in the oyster. Indeed, though our MeDIP-seq results confirm predominant intragenic methylation, the profiles depend on the oyster's developmental and reproductive stage. We discuss the perspective that oyster DNA methylation could be biased toward the 5'-end of some genes, depending on physiological status, suggesting important functional outcomes of putative promoter methylation from cell differentiation during early development to sustained adaptation of the species to the environment.
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