ArticleJapanese journal of ophthalmology2014
Vision-related quality of life and visual function following intravitreal bevacizumab injection for persistent diabetic macular edema after vitrectomy.
Article in Japanese journal of ophthalmology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Efficacy and safety of the dexamethasone implant in vitrectomized and nonvitrectomized eyes with diabetic macular edema: A systematic review and meta-analysis.Frontiers in pharmacology · 2022Pooled it
- The Effect of Telenursing Using Self-care Education Podcasts on Anxiety and Quality of Life of Patients with Diabetic Retinopathy Undergoing Intravitreal Injection: A Randomized Clinical Trail.International journal of community based nursing and midwifery · 2026Trial
- Vitrectomy Status Alters Early Intravitreal Drug Distribution: An Ex Vivo PET-CT Study.Investigative ophthalmology & visual science · 2026Article
- Structure-function associations between contrast sensitivity and widefield swept-source optical coherence tomography angiography in diabetic macular edema.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023Observational
- Changes in metamorphopsia following intravitreal aflibercept injection for diabetic macular edema.Scientific reports · 2022Article
- Time course of changes in vision-related quality of life following intravitreal ranibizumab treatment for branch retinal vein occlusion.Scientific reports · 2022Observational
- Relationship between stereopsis and vision-related quality of life in patients with branch retinal vein occlusion.BMJ open ophthalmology · 2022Observational
- Real-World Evidence in the Management of Diabetic Macular Edema with Intravitreal Anti-VEGFs in Asia: A Systematic Literature Review.Clinical ophthalmology (Auckland, N.Z.) · 2022Review
- Prospective study of morphologic and functional parameter changes post intravitreal therapy for macular edema.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2020Article
- Correlation between metamorphopsia and disorganization of the retinal inner layers in eyes with diabetic macular edema.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2019Article
- Patient-reported prevalence of metamorphopsia and predictors of vision-related quality of life in vitreomacular traction: a prospective, multi-centre study.Eye (London, England) · 2019Article
- Burden Of Treatment Among Patients Undergoing Intravitreal Injections For Diabetic Macular Oedema In Australia.Diabetes, metabolic syndrome and obesity : targets and therapy · 2019Article
- Comparison of efficacy of intravitreal ranibizumab between non-vitrectomized and vitrectomized eyes with diabetic macular edema.International ophthalmology · 2018Article
- Evaluation of Vitrectomy with Planned Foveal Detachment as Surgical Treatment for Refractory Diabetic Macular Edema with or without Vitreomacular Interface Abnormality.Journal of ophthalmology · 2018Article
- Management of diabetic macular edema in Japan: a review and expert opinion.Japanese journal of ophthalmology · 2018Review
- Health-related quality of life, visual function and treatment satisfaction following intravitreal dexamethasone implant for diabetic macular edema.Patient preference and adherence · 2017Article
- Relationship between metamorphopsia and foveal microstructure in patients with branch retinal vein occlusion and cystoid macular edema.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2016Article
- Article
- Planned foveal detachment technique for the resolution of diffuse diabetic macular edema.Japanese journal of ophthalmology · 2015Article
- Association Between Contrast Sensitivity and Central Subfield Thickness in Center-Involving Diabetic Macular Edema.Journal of vitreoretinal diseasesArticle
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo investigate the vision-related quality of life (VR-QOL) and visual function in patients undergoing intravitreal injection of bevacizumab (IVB) for persistent diabetic macular edema (DME) after vitrectomy.
methodsThis institutional study enrolled 20 consecutive patients (20 eyes) who had received 1.25 mg IVB for persistent macular edema after vitrectomy for DME at least 3 months previously. Visual function and VR-QOL were measured before, and 1 and 3 months after IVB. Measurements included the logarithm of the minimum angle of resolution (logMAR), best corrected visual acuity (BCVA), letter contrast sensitivity, severity of metamorphopsia using M-CHARTS, central retinal thickness using optical coherence tomography, and VR-QOL with the 25-item National Eye Institute Visual Function Questionnaire (VFQ-25).
resultsOne month after IVB, statistically significant improvements were observed in central retinal thickness, letter contrast sensitivity, and the VFQ-25 "mental health" subscale score (P < 0.05, Dunnett test). LogMAR BCVA, metamorphopsia, and the VFQ-25 composite score did not improve significantly. Three months after IVB, there were no significant improvements in any parameters examined.
conclusionsIntravitreal bevacizumab injection for persistent DME after vitrectomy temporarily improved central retinal thickness, contrast sensitivity, and the psychometric aspect of the VR-QOL, but these effects did not last for over 3 months.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.