ArticleScientific reports2014
Diagnosis of snake envenomation using a simple phospholipase A2 assay.
Article in Scientific reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 47 citations in OpenAlex.
- Diagnosis of Indian Big Four and monocled Cobra snakebites in envenomed plasma using smartphone-based digital imaging colourimetry method.PLoS neglected tropical diseases · 2025Article
- Biomarkers in Snakebite: Will This be a Reality in Near Future?Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2025Article
- Antivenom availability, delays and use in Australia.Toxicon: X · 2023Article
- Snake Venom-specific Phospholipase A2: A Diagnostic Marker for the Management of Snakebite Cases.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2022Article
- Cytotoxin antibody-based colourimetric sensor for field-level differential detection of elapid among big four snake venom.PLoS neglected tropical diseases · 2021Article
- Clinical management of snakebite envenoming: Future perspectives.Toxicon: X · 2021Article
- Snakebite Envenoming Diagnosis and Diagnostics.Frontiers in immunology · 2021Review
- Circulating Secretory Phospholipase A2 Activity following Snakebites and Its Relationship with Envenomation Status and Progression of Local Swelling.The American journal of tropical medicine and hygiene · 2020Article
- Time delays in treatment of snakebite patients in rural Sri Lanka and the need for rapid diagnostic tests.PLoS neglected tropical diseases · 2020Article
- Phospholipase A2 (PLABiomedicines · 2020Article
- Current Knowledge on Snake Dry Bites.Toxins · 2020Review
- Oxidative stress and antioxidant defense in detoxification systems of snake venom-induced toxicity.The journal of venomous animals and toxins including tropical diseases · 2020Article
- Enzyme immunoassays for detection and quantification of venoms of Sri Lankan snakes: Application in the clinical setting.PLoS neglected tropical diseases · 2020Article
- Bedside Coagulation Tests in Diagnosing Venom-Induced Consumption Coagulopathy in Snakebite.Toxins · 2020Review
- Collocation of avian and mammal antibodies to develop a rapid and sensitive diagnostic tool for Russell's Vipers Snakebite.PLoS neglected tropical diseases · 2020Article
- A Review and Database of Snake Venom Proteomes.Toxins · 2017Review
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diagnosis of snake envenomation is challenging but critical for deciding on antivenom use. Phospholipase A2 enzymes occur commonly in snake venoms and we hypothesized that phospholipase activity detected in human blood post-bite may be indicative of envenomation. Using a simple assay, potentially a bedside test, we detected high phospholipase activity in sera of patients with viper and elapid envenomation compared to minimal activity in non-envenomed patients.
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Registered trials
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