ArticleNature methods2014
Chronic, wireless recordings of large-scale brain activity in freely moving rhesus monkeys.
Article in Nature methods, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03811301 (Neurodevice Phase I), which is not on this map. Cited by 137 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neurodevice Phase I: Wireless Implantable Neurodevice Microsystem for Neuroprosthesis and Neuroscience
Who cites it
137 citing papers in PubMed, 366 citations in OpenAlex.
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- High-channel-count neural recording and stimulation platform with 5,376 simultaneous recording channels.bioRxiv : the preprint server for biology · 2026Article
- A Comb-Shaped Flexible Microelectrode Array for Simultaneous Multi-Scale Cortical Recording.Micromachines · 2026Article
- Deciphering Neural Mechanisms Underlying Marmoset Dynamic Natural Behaviors Using a Miniaturized Wireless Large-Scale Coverage Neural Recorder.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- A method for efficient, rapid, and minimally invasive implantation of individual non-functional motes with penetrating subcellular-diameter carbon fiber electrodes into rat cortex.Frontiers in neuroscience · 2026Article
- A wireless subdural-contained brain-computer interface with 65,536 electrodes and 1,024 channels.Nature electronics · 2025Article
- Large-scale high-density brain-wide neural recording in nonhuman primates.Nature neuroscience · 2025Article
- A stealthy neural recorder for the study of behaviour in primates.Nature biomedical engineering · 2025Article
- Home-Cage Training for Non-Human Primates: An Opportunity to Reduce Stress and Study Natural Behavior in Neurophysiology Experiments.Animals : an open access journal from MDPI · 2025Review
- Article
- Stable, chronic in-vivo recordings from a fully wireless subdural-contained 65,536-electrode brain-computer interface device.bioRxiv : the preprint server for biology · 2025Article
- Compact and low-power wireless headstage for electrocorticography recording of freely moving primates in a home cage.Frontiers in neuroscience · 2025Article
- Building egocentric models of local space from retinal input.Current biology : CB · 2024Review
- Investigation of mutation spectrum amongst patients with familial primary cardiomyopathy using targeted NGS in Indian population.Journal of applied genetics · 2024Article
- Surface-Grafted Biocompatible Polymer Conductors for Stable and Compliant Electrodes for Brain Interfaces.Advanced healthcare materials · 2024Article
- A Spatially Diverse 2TX-3RX Galvanic-Coupled Transdural Telemetry for Tether-Less Distributed Brain-Computer Interfaces.IEEE transactions on biomedical circuits and systems · 2024Article
- A high-density 1,024-channel probe for brain-wide recordings in non-human primates.Nature neuroscience · 2024Article
- Intan Technologies integrated circuits can produce analog-to-digital conversion artifacts that affect neural signal acquisition.Journal of neural engineering · 2024Article
- Power-integrated, wireless neural recording systems on the cranium using a direct printing method for deep-brain analysis.Science advances · 2024Article
77 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 2 institutions in 1 country.
Funding
Abstract
Advances in techniques for recording large-scale brain activity contribute to both the elucidation of neurophysiological principles and the development of brain-machine interfaces (BMIs). Here we describe a neurophysiological paradigm for performing tethered and wireless large-scale recordings based on movable volumetric three-dimensional (3D) multielectrode implants. This approach allowed us to isolate up to 1,800 neurons (units) per animal and simultaneously record the extracellular activity of close to 500 cortical neurons, distributed across multiple cortical areas, in freely behaving rhesus monkeys. The method is expandable, in principle, to thousands of simultaneously recorded channels. It also allows increased recording longevity (5 consecutive years) and recording of a broad range of behaviors, such as social interactions, and BMI paradigms in freely moving primates. We propose that wireless large-scale recordings could have a profound impact on basic primate neurophysiology research while providing a framework for the development and testing of clinically relevant neuroprostheses.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.