ArticleBMC gastroenterology2014
Clinical predictors of incident gallstone disease in a Chinese population in Taipei, Taiwan.
Article in BMC gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 3 of them syntheses that pooled it.
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Who cites it
27 citing papers in PubMed, 3 syntheses or guidelines pooled it, 51 citations in OpenAlex.
- Estimating global prevalence of gallbladder stones in general population from 2000 to 2024: systematic review and meta-analysis.Annals of medicine · 2025Pooled it
- Significant Association Between Gallstone Disease and Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis.Digestive diseases and sciences · 2016Pooled it
- Body mass index, abdominal fatness and the risk of gallbladder disease.European journal of epidemiology · 2015Pooled it
- A retrospective observational study: are gallstone patients aging, or are the elderly more susceptible to gallstones?BMC gastroenterology · 2026Observational
- Prevalence and risk factors of cholelithiasis in patients with spinal cord injury: A cross-sectional analysis.PloS one · 2026Article
- Metabolic abnormalities, liver enzymes increased risk of gallstones: a cross-sectional study and multivariate mendelian randomization analysis.Internal and emergency medicine · 2025Article
- Comparison of Triglyceride-Glucose Index between Patients with Gallstone and Healthy Individuals.Iranian journal of public health · 2024Article
- [New Progress in Longitudinal Research on the Risk Factors for Cholelithiasis].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2024Review
- The Mitochondrial tRNAFrontiers in genetics · 2022Article
- Risk of gallstones based on ABCG8 rs11887534 single nucleotide polymorphism among Taiwanese men and women.BMC gastroenterology · 2021Article
- An inverse association of weight and the occurrence of asymptomatic gallbladder stone disease in hypercholesterolemia patients: a case-control study.Lipids in health and disease · 2020Article
- Relationship between high-sensitivity C reactive protein and the risk of gallstone disease: results from the Kailuan cohort study.BMJ open · 2020Article
- The Association Between Cholecystectomy, Metabolic Syndrome, and Nonalcoholic Fatty Liver Disease: A Population-Based Study.Clinical and translational gastroenterology · 2020Article
- Strong association between metabolically-abnormal obesity and gallstone disease in adults under 50 years.BMC gastroenterology · 2019Article
- Article
- Moderate, but not heavy, tea drinking decreased the associated risk of gallstones in a Taiwanese population.European journal of clinical nutrition · 2019Article
- Bidirectional Association between Nonalcoholic Fatty Liver Disease and Gallstone Disease: A Cohort Study.Journal of clinical medicine · 2018Article
- Acute biliary events during anti-tuberculosis treatment: hospital case series and a nationwide cohort study.BMC infectious diseases · 2018Article
- Association between different combination of measures for obesity and new-onset gallstone disease.PloS one · 2018Article
- Interval increase in the prevalence of symptomatic cholelithiasis-associated non-alcoholic fatty liver disease over a ten-year period in an Asian population.Singapore medical journal · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGallstone disease (GSD) is a common gastrointestinal disorder throughout the world. The authors explored the incidence of GSD in Taiwan and its condition-associated predictive factors.
methodsThe initial study cohort comprised 2386 healthy adult participants, who were voluntarily admitted to a teaching hospital for a physical check-up in 2002 in Taipei, Taiwan. After excluding 126 patients who exhibited prevalent GSD, 2260 non-GSD participants received annual follow-up screenings for GSD until 31 December, 2007. Of those, 1296 (57.3%) patients were re-examined to collect blood samples and conduct ultrasound sonography.
resultsAmong the 1296 participants who exhibited no GSD at the first screening, 23 patients developed GSD during 3640 person-years of follow-up. The incidence was 0.632% per year (95% CI: 0.292%-2.009%). After conducting a Cox regression, increased age (50-59 years versus < 40 years, RR = 2.16 [95% CI: 1.09-5.97], 60+ years versus < 40 years, RR = 3.81 [95% CI: 2.77-8.63]), high body mass index (≥27 kg/m2 versus < 24 kg/m2, RR = 1.64 [95% CI: 1.07-2.98]), high fasting plasma glucose levels (≥126 mg/dL versus < 110 mg/dL, RR = 1.68, 95% CI: 1.10-3.87), and nonalcoholic fatty liver disease (yes versus no, RR = 1.44, 95% CI: 1.21-1.90) appeared to be significantly related to developing GSD.
conclusionIncreased age is a well-established risk factor for developing GSD. The current findings indicated that high body mass index, elevated fasting plasma glucose levels, and nonalcoholic fatty liver disease were also associated with GSD.
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