ReviewExpert opinion on pharmacotherapy2014
Pharmacotherapy of postpartum depression: an update.
Review in Expert opinion on pharmacotherapy, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05046405 (Home-based Transcranial Direct Current Stimulation in Postpartum Depression), which is not on this map. Cited by 27 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Home-based Transcranial Direct Current Stimulation in Postpartum Depression: the Feasibility Study and Pilot Study
Who cites it
27 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Neural correlates of peripartum depression: a systematic review, meta-analysis and comparison to major depressive disorder.Molecular psychiatry · 2025Pooled it
- Brexanolone in Postpartum Depression:Journal of women's health (2002) · 2021Pooled it
- Canadian Network for Mood and Anxiety Treatments (CANMAT) 2016 Clinical Guidelines for the Management of Adults with Major Depressive Disorder: Section 6. Special Populations: Youth, Women, and the Elderly.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2016Pooled it
- Transdermal estradiol for postpartum depression: results from a pilot randomized, double-blind, placebo-controlled study.Archives of women's mental health · 2020Trial
- Open-label, proof-of-concept study of brexanolone in the treatment of severe postpartum depression.Human psychopharmacology · 2017Trial
- Understanding and Addressing Male Postpartum Depression: Incidence, Causes, Diagnosis, and Management Strategies.Medical science monitor : international medical journal of experimental and clinical research · 2024Review
- An investigation of knowledge and attitudes towards antidepressants: a cross-sectional survey of Jordan's six medical schools.BMC psychiatry · 2023Article
- Review
- Article
- Associations between commonly used patient-reported outcome tools in postpartum depression clinical practice and the Hamilton Rating Scale for Depression.Archives of women's mental health · 2020Article
- Toward a framework for best practices and research guidelines for perinatal depression research.Journal of neuroscience research · 2020Review
- The effects of pre- and post-partum depression on child behavior and psychological development from birth to pre-school age: a protocol for a systematic review and meta-analysis.Systematic reviews · 2020Article
- The role of allopregnanolone in depressive-like behaviors: Focus on neurotrophic proteins.Neurobiology of stress · 2020Article
- Cost-Effectiveness of Brexanolone Versus Selective Serotonin Reuptake Inhibitors for the Treatment of Postpartum Depression in the United States.Journal of managed care & specialty pharmacy · 2020Article
- Is Postpartum Depression Different From Depression Occurring Outside of the Perinatal Period? A Review of the Evidence.Focus (American Psychiatric Publishing) · 2020Review
- Intravenous brexanolone for postpartum depression: what it is, how well does it work, and will it be used?Therapeutic advances in psychopharmacology · 2020Review
- Use of Brexanolone for Postpartum Depression.Innovations in clinical neuroscience · 2019Review
- Article
- Maternal depression treatment in HIV (M-DEPTH): Study protocol for a cluster randomized controlled trial.Medicine · 2019Article
- Postpartum Depression in Men.Innovations in clinical neuroscience · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
introductionPostpartum depression (PPD) is a common and serious illness that affects up to 14% of women in the first month after childbirth. We present an update on the pharmacologic treatment of PPD, although there continues to be a lack of large, randomized controlled trials (RCTs). AREAS COVERED: A review of the literature on the use of antidepressants, hormonal supplements and omega-3 fatty acids for the prevention and the treatment of PPD published since the original review in 2009 and the authors' opinion on the current status of the pharmacological treatment of PPD are covered. An electronic search was performed by using PubMed, Medline and PsychINFO. Inclusion criteria were: i) empirical articles in peer-reviewed English-language journals; ii) well-validated measures of depression; and iii) a uniform scoring system for depression among the sample. EXPERT OPINION: Since the last Expert Opinion review, four antidepressant treatment studies and one prevention study of PPD have been published. Six RCTs evaluating the use of omega-3 fatty acids (four for prevention and two for treatment) have been published. There continues to be lack of data regarding the pharmacotherapy of PPD. However, serotonin reuptake inhibitors should be considered first-line for women with PPD after it has been determined that the proper diagnosis is not bipolar disorder. It is important to individualize treatment for women with PPD and consider the risks and benefits of treatment while breastfeeding.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.