Evidence map›Paper›PMID 24772439›Full record

ReviewBioMed research international2014

Estimating glomerular filtration rate in older people.

Sabrina Garasto, Sergio Fusco, Francesco Corica, Maria Rosignuolo, Antonio Marino, Alberto Montesanto, Francesco De Rango, Marcello Maggio, Vincenzo Mari, Andrea Corsonello and 1 more

Open access · hybridAbstract readReview
In one paragraph

Review in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 74 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Sabrina GarastoUnit of Geriatric Pharmacoepidemiology, Italian National Research Center on Aging (INRCA), C. da Muoio Piccolo, 87100 Cosenza, Italy.ORCID 0000-0001-7207-3127
Sergio FuscoUnit of Geriatric Pharmacoepidemiology, Italian National Research Center on Aging (INRCA), C. da Muoio Piccolo, 87100 Cosenza, Italy ; Department of Clinical and Experimental Medicine, University of Messina, 98122 Messina, Italy.
Francesco CoricaDepartment of Clinical and Experimental Medicine, University of Messina, 98122 Messina, Italy.
Maria RosignuoloUnit of Geriatric Pharmacoepidemiology, Italian National Research Center on Aging (INRCA), C. da Muoio Piccolo, 87100 Cosenza, Italy.ORCID 0000-0001-7506-7101
Antonio MarinoUnit of Geriatric Pharmacoepidemiology, Italian National Research Center on Aging (INRCA), C. da Muoio Piccolo, 87100 Cosenza, Italy.
Alberto MontesantoDepartment of Cell Biology, University of Calabria, 87036 Rende, Italy.ORCID 0000-0002-3219-5370
Francesco De RangoDepartment of Cell Biology, University of Calabria, 87036 Rende, Italy.ORCID 0000-0001-8325-4812
Marcello MaggioDepartment of Geriatric Rehabilitation, University-Hospital of Parma and Section of Geriatrics, Department of Clinical and Experimental Medicine, University of Parma, 43100 Parma, Italy.
Vincenzo MariUnit of Clinical Pathology, Italian National Research Center on Aging (INRCA), 87100 Cosenza, Italy.
Andrea CorsonelloUnit of Geriatric Pharmacoepidemiology, Italian National Research Center on Aging (INRCA), C. da Muoio Piccolo, 87100 Cosenza, Italy.
Fabrizia LattanzioScientific Direction, Italian National Research Center on Aging (INRCA), 60127 Ancona, Italy.ORCID 0000-0003-4051-1289
Istituto Nazionale di Riposo e Cura per Anziani · ITUniversity of Calabria · ITUniversity of Messina · ITUniversity of Parma · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We aimed at reviewing age-related changes in kidney structure and function, methods for estimating kidney function, and impact of reduced kidney function on geriatric outcomes, as well as the reliability and applicability of equations for estimating glomerular filtration rate (eGFR) in older patients. CKD is associated with different comorbidities and adverse outcomes such as disability and premature death in older populations. Creatinine clearance and other methods for estimating kidney function are not easy to apply in older subjects. Thus, an accurate and reliable method for calculating eGFR would be highly desirable for early detection and management of CKD in this vulnerable population. Equations based on serum creatinine, age, race, and gender have been widely used. However, these equations have their own limitations, and no equation seems better than the other ones in older people. New equations specifically developed for use in older populations, especially those based on serum cystatin C, hold promises. However, further studies are needed to definitely accept them as the reference method to estimate kidney function in older patients in the clinical setting.

Indexed as

Glomerular Filtration RateAgedAged, 80 and overAgingFemaleHumansMale

Identifiers

PMID24772439
PMCPMC3977451
OpenAlexW2079450620

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.