Evidence map›Paper›PMID 24772434›Full record

Trial reportBioMed research international2014

Resistance to erythropoiesis-stimulating agents is associated with arterial microcalcification in early hemodialysis patients.

Hye Sung Won, Su Jin Choi, Yu Seon Yun, Ok-Ran Shin, Yoon Ho Ko, Young Soo Kim, Sun Ae Yoon, Young Ok Kim

Open access · hybridAbstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Hye Sung WonDepartment of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Su Jin ChoiDepartment of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Yu Seon YunDepartment of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Ok-Ran ShinDepartment of Pathology, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Yoon Ho KoDepartment of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Young Soo KimDepartment of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Sun Ae YoonDepartment of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Young Ok KimDepartment of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea ; Division of Nephrology, Department of Internal Medicine, Uijeongbu St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 271 Cheon bo-ro, Uijeongbu-si, Gyeonggi-do 480-717, Republic of Korea.
Catholic University of Korea · KRThe Catholic University of Korea Uijeongbu St. Mary's Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to evaluate the relationship between arterial microcalcification (AMiC) and erythropoiesis-stimulating agents (ESA) hyporesponsiveness in hemodialysis patients. The presence of AMiC was confirmed by pathologic examination of von Kossa-stained arterial specimens acquired during vascular access surgery. We assessed the ESA hyporesponsiveness index (EHRI), defined as the weekly ESA dose per kilogram body weight divided by the hemoglobin level. AMiC was detected in 33 (40.2%) of 82 patients. Patients with diabetes had a higher incidence of AMiC than patients without diabetes. The serum levels of albumin and cholesterol were higher in patients without AMiC than in patients with AMiC. The serum levels of intact parathyroid hormone were lower in patients with AMiC than in patients without AMiC. The serum levels of phosphate and calcium-phosphorus product did not differ between the two groups. The mean EHRI value was higher in patients with AMiC than in patients without AMiC. In multivariate analyses, ESA hyporesponsiveness and diabetes showed a significant association with AMiC. In conclusion, ESA hyporesponsiveness may be a clinical relevant parameters related to AMiC in hemodialysis patients.

Indexed as

Drug ResistanceRenal DialysisAdultAgedAged, 80 and overArteriesDiabetes ComplicationsFemaleFollow-Up StudiesHematinicsHumansMaleMiddle AgedParathyroid HormoneRetrospective StudiesVascular CalcificationHematinicsParathyroid Hormone

Identifiers

PMID24772434
PMCPMC3977079
OpenAlexW2064909091

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.