ArticleJournal of gastrointestinal oncology2014
Safety and efficacy of esophageal stents preceding or during neoadjuvant chemotherapy for esophageal cancer: a systematic review and meta-analysis.
Article in Journal of gastrointestinal oncology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 77 citations in OpenAlex.
- Meta-Analysis of the Effect of Dietary Care on Nausea and Vomiting in Oncology Chemotherapy Patients.Contrast media & molecular imaging · 2022Pooled it
- From Migration to Emergency: A Systematic Review of Acute Presentations Following Late Esophageal Stent Migration.Journal of clinical medicine · 2026Review
- Article
- German guidelines for the diagnosis and treatment of squamous-cell carcinoma and adenocarcinoma of the esophagus-version 4.0.ESMO gastrointestinal oncology · 2025Review
- Gastric transcatheter chemoembolization combined with systemic chemotherapy vs. systemic chemotherapy alone for patients with advanced gastric cardiac cancer presenting with dysphagia: A case control study.Oncology letters · 2024Article
- Self-expandable metallic stent-induced esophagorespiratory fistulas in patients with advanced esophageal cancer.Clinical endoscopy · 2023Article
- How to reduce fistula formation after self-expandable metallic stent insertion for treating malignant esophageal stricture?Clinical endoscopy · 2023Article
- Best Practices in Esophageal, Gastroduodenal, and Colonic Stenting.GE Portuguese journal of gastroenterology · 2023Review
- Nutritional Status and the Outcomes of Endoscopic Stenting in Benign and Malignant Diseases of Esophagus.Nutrients · 2023Article
- Total endoluminal repair of aorto-oesophageal fistula.BMJ case reports · 2022Article
- Recent Updates in Gastrointestinal Stent Placement from the Esophagus to the Colon: A Radiological Perspective.Cardiovascular and interventional radiology · 2022Review
- Treatment mode and prognosis of esophageal perforation after radiotherapy in patients with esophageal carcinoma.Frontiers in oncology · 2022Article
- Self-expandable metal stents in esophageal cancer before preoperative neoadjuvant therapy: efficacy, safety, and long-term outcomes.Surgical endoscopy · 2021Article
- [Endoscopic Management of Dysphagia].The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2021Review
- Article
- Optimizing health before elective thoracic surgery: systematic review of modifiable risk factors and opportunities for health services research.Journal of thoracic disease · 2019Review
- Computed tomography volumetry of esophageal cancer - the role of semiautomatic assessment.BMC medical imaging · 2019Article
- Oesophageal Stents for Potentially Curable Oesophageal Cancer - A Bridge to Surgery?The Ulster medical journal · 2019Review
- Esophageal Metal Stents with Concurrent Chemoradiation Therapy for Locally Advanced Esophageal Cancer: Safe or Not?The oncologist · 2018Article
- Self-Expandable Metallic Stent Placement for the Palliation of Esophageal Cancer.Journal of Korean medical science · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPatients with locally advanced esophageal cancer who require neoadjuvant therapy have significant dysphagia and may severely impair nutritional status. We conducted a meta-analysis to assess the efficacy of self-expandable metal stents prior to neoadjuvant therapy.
methodsA systematic search was conducted using MEDLINE, PubMed, EMBASE, Current Contents Connect, Cochrane library, Google Scholar, Science Direct, and Web of Science. Original data was abstracted from each study and used to calculate a pooled odd ratio (OR) and 95% confidence interval (95% CI).
resultsOnly nine studies comprising of 180 patients were included for analysis. The overall procedural success rate was 95% (95% CI, 0.895-0.977). There was a substantial decrease in the dysphagia scores standard difference in means (SDM) -0.81 [standard error (SE) 0.15, 95% CI, -1.1 to -0.51], similar increase in weight SDM 0.591 (SE 0.434, 95% CI, -0.261 to 1.442) and serum albumin SDM 0.35 (SE 0.271, 95% CI, -0.181 to 0.881). The incidence of major adverse events included stent migration 32% (95% CI, 0.258-0.395) and chest discomfort 51.4% (95% CI, 0.206-0.812).
conclusionsPlacement of stents in patients with locally advanced esophageal cancer significantly improves dysphagia and allows for oral nutrition during neoadjuvant therapy. Stents appear to be effective for palliating dysphagia. Stent migration was a common occurrence; however, migration may be a sign of tumor response to neoadjuvant therapy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.