Evidence map›Paper›PMID 24772035›Full record

ArticleTheScientificWorldJournal2014

Evaluation the surface antigen of the Salmonella typhimurium ATCC 14028 ghosts prepared by "SLRP".

Amara A Amro, Ahmed J Neama, Ahmed Hussein, Emad A Hashish, Salah A Sheweita

Open access · goldAbstract readEvaluation Study
In one paragraph

Article in TheScientificWorldJournal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 22 citations in OpenAlex.

  1. A Chemically InducedVaccines · 2026
    Article
  2. Article
  3. Protective Immunity againstInternational journal of molecular sciences · 2022
    Article
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Amara A AmroDepartment of Protein Research, Genetic Engineering and Biotechnology Research Institute, City for Scientific Research and Technology Applications, New Borg Al-Arab, P.O. Box. 21934, Alexandria, Egypt ; Biotechnology Department, Institute of Graduate Studies & Research, Alexandria University, 163 El Horreya Avenu, P.O. Box 832, Alexandria 21526, Egypt.
Ahmed J NeamaZoonoses Research Unit, Faculty of Veterinary Medicine, Alqadisya University, Alqadisya, Iraq.
Ahmed HusseinBiotechnology Department, Institute of Graduate Studies & Research, Alexandria University, 163 El Horreya Avenu, P.O. Box 832, Alexandria 21526, Egypt.
Emad A HashishDepartment of Clinical Pathology, Faculty of Veterinary Medicine, Zagazig University, Zagazig, Egypt.
Salah A SheweitaBiotechnology Department, Institute of Graduate Studies & Research, Alexandria University, 163 El Horreya Avenu, P.O. Box 832, Alexandria 21526, Egypt.
Alexandria University · EGCity of Scientific Research and Technological Applications · EGUniversity of Al-Qadisiyah · IQZagazig University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, bacterial ghosts (BGs) were prepared using a protocol based on critical chemical concentrations. It has been given the name "sponge like" (SL) protocol and used in its reduced form "sponge like reduced protocol" (SLRP). While specific antibody for Salmonella is available on the market under the commercial names (of some kits) such as Febrile Antigen Kit (N.S. BIO-TEC), we used the described Kit to investigate the validity of the SLRP. In this study, using SLRP we succeeded to prepare STGs with correct surface antigens could interact with their specific antibodies. Additionally the study has included oral vaccination with STGs with challenge test. The rats serums have been evaluated against both of the O and H antigens. The antigen-antibody interaction (agglutination) results of both the SLRP and the animal experiments prove that we have correct STGs able to immunize the rats against viable Salmonella. STGs could be used as vaccine and as adjuvant and in the antibodies and in the diagnostic kits production. This study is an additional step for the establishment of correct BGs for immunological purposes.

Indexed as

AnimalsAntibodies, BacterialAntigens, BacterialAntigens, SurfaceBacterial VaccinesCell FractionationCell MembraneMaleMicroscopy, ElectronO AntigensRats, Sprague-DawleyReagent Kits, DiagnosticReproducibility of ResultsSalmonella typhimuriumVaccinationAntibodies, BacterialAntigens, BacterialAntigens, SurfaceBacterial VaccinesH antigenO AntigensReagent Kits, Diagnostic

Identifiers

PMID24772035
PMCPMC3977473
OpenAlexW2031137062

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.