ArticleEuropean journal of organic chemistry2013
Generation of Trityl Radicals by Nucleophilic Quenching of Tris(2,3,5,6-tetrathiaaryl)methyl Cations and Practical and Convenient Large-Scale Synthesis of Persistent Tris(4-carboxy-2,3,5,6-tetrathiaaryl)methyl Radical.
Article in European journal of organic chemistry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Synthesis and Characterization of Pyridine-Containing Tetrathiatriarylmethyl (TAM) Stable Radicals for Biomedical Magnetic Resonance Applications.The Journal of organic chemistry · 2026Article
- Paramagnetic Agents for SE DNP: Synthesis and ESR Characterization of New Lipophilic Derivatives of Finland Trityl.Molecules (Basel, Switzerland) · 2025Article
- Line-Shifting Triarylmethyl Radicals for Imaging of Enzyme Activity Using Overhauser-Enhanced Magnetic Resonance Imaging: Application to Alkaline Phosphatase.Chemical & biomedical imaging · 2025Article
- Biocompatible Monophosphonated Trityl Spin Probe, HOPE71, for In Vivo Measurement of pOAnalytical chemistry · 2023Article
- Synthesis and characterization of a Cu(ii) coordination-containing TAM radical as a nitroxyl probe.RSC advances · 2022Article
- Large-scale synthesis of a monophosphonated tetrathiatriarylmethyl spin probe for concurrentRSC advances · 2021Article
- Compaction of RNA Duplexes in the Cell*.Angewandte Chemie (International ed. in English) · 2020Article
- AAngewandte Chemie (International ed. in English) · 2020Article
- Synthesis, Characterization, and Application of a Highly Hydrophilic Triarylmethyl Radical for Biomedical EPR.The Journal of organic chemistry · 2020Article
- Improved, Odorless Access to Benzo[1,2-d;4,5-d']- bis[1,3]dithioles andMolecules (Basel, Switzerland) · 2020Article
- Site Selective and Efficient Spin Labeling of Proteins with a Maleimide-Functionalized Trityl Radical for Pulsed Dipolar EPR Spectroscopy.Molecules (Basel, Switzerland) · 2019Article
- Three-spin solid effect and the spin diffusion barrier in amorphous solids.Science advances · 2019Article
- Feasibility of in vivo three-dimensional TMagma (New York, N.Y.) · 2017Article
- Triarylmethyl Radicals: EPR Study ofZeitschrift fur physikalische Chemie (Frankfurt am Main, Germany) · 2017Article
- Trityl-based alkoxyamines as NMP controllers and spin-labels.Polymer chemistry · 2016Article
- Electron spin dynamics and spin-lattice relaxation of trityl radicals in frozen solutions.Physical chemistry chemical physics : PCCP · 2016Article
- Facile and High-Yielding Synthesis of TAM Biradicals and Monofunctional TAM Radicals.Synlett : accounts and rapid communications in synthetic organic chemistry · 2016Article
- Room-Temperature Electron Spin Relaxation of Triarylmethyl Radicals at the X- and Q-Bands.The journal of physical chemistry. B · 2015Article
- Preparation of Diversely Substituted Triarylmethyl Radicals by the Quenching of Tris(2,3,5,6-tetrathiaaryl)methyl Cations with C-, N-, P-, and S-Nucleophiles.European journal of organic chemistry · 2014Article
- Characterization of the Binding of the Finland Trityl Radical with Bovine Serum Albumin.RSC advances · 2014Article
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Authors and funding
7 authors.
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Abstract
Tris(2,3,5,6-tetrathiaaryl)methyl cations, which were generated from the corresponding triarylmethanols in the presence of strong acids, underwent reaction with nucleophiles to give trityl radicals, as the product of a one-electron reduction of the carbocation. Depending on the nature of the nucleophile, the only byproducts were either diamagnetic quinone methides or asymmetrical monosubstituted trityl radicals. Herein, we report a protocol for the large-scale synthesis of the Finland trityl, which has the advantage of high overall yield and reproducibility.
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