Evidence map›Paper›PMID 24771966›Full record

ArticleLaser therapy2014

Effect of Stress-free Therapy on Cerebral Blood Flow: Comparisons among patients with metabolic cardiovascular disease, healthy subjects and placebo-treated subjects.

Kenji Ryotokuji, Keisou Ishimaru, Kazuhiko Kihara, Yoshihisa Namiki, Takuma Nakashima, Satoru Otani

Open access · diamondAbstract read
In one paragraph

Article in Laser therapy, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Kenji RyotokujiFaculty of Health Sciences, Ryotokuji University, Urayasu, Japan.
Keisou IshimaruFaculty of Health Sciences, Ryotokuji University, Urayasu, Japan.
Kazuhiko KiharaFaculty of Health Sciences, Ryotokuji University, Urayasu, Japan.
Yoshihisa NamikiFaculty of Health Sciences, Ryotokuji University, Urayasu, Japan.
Takuma NakashimaFaculty of Health Sciences, Ryotokuji University, Urayasu, Japan.
Satoru OtaniFaculty of Health Sciences, Ryotokuji University, Urayasu, Japan.
Ryotokuji University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsWe have developed a Stress-free Therapy(®) device wherein "Pinpoint Plantar Long-wavelength Infrared Light Irradiation (PP-LILI)" increases peripheral-deep body temperature and blood flow volume and stabilizes blood pressure as well as significantly reduces stress hormones such as adrenocorticotrophic hormone and cortisol without using drugs. Moreover, we have found this therapy to significantly improve blood glucose and insulin resistance in patients with type 2 diabetes. Based on this background of clinical efficacy, we validated changes in cerebral blood flow in patients with metabolic cardiovascular disease and examined the efficacy of Stress-free Therapy(®) on cerebral blood flow as compared to that in healthy control subjects and placebo-treated patients.

resultsThe change in cerebral blood flow volume during 15-minute PP-LILI was 5.1 ± 1.8 mL/min in patients with metabolic cardiovascular disease, showing a significant increase (P<0.05) of 3.1 mL/min as compared with the mean blood flow value after resting for 15 minutes.

conclusionsOur results suggested Stress-free Therapy(®) to significantly increase cerebral blood flow, possibly leading to the prevention of metabolic cardiovascular disease.

Identifiers

PMID24771966
PMCPMC3999433
OpenAlexW2030028334

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.