ArticleGeburtshilfe und Frauenheilkunde2013
Adenomyosis: Epidemiology, Risk Factors, Clinical Phenotype and Surgical and Interventional Alternatives to Hysterectomy.
Article in Geburtshilfe und Frauenheilkunde, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
77 citing papers in PubMed, 2 syntheses or guidelines pooled it, 205 citations in OpenAlex.
- Association of Uterine Tissue Innervation and Peripheral Nerve Density with Adenomyosis Related Pain. A Systematic Review.Reproductive sciences (Thousand Oaks, Calif.) · 2024Pooled it
- Evaluation of pharmacological interventions in the management of adenomyosis: a systematic review.European journal of clinical pharmacology · 2022Pooled it
- Uterine artery embolization for the treatment of symptomatic adenomyosis: a systematic review.CVIR endovascular · 2026Review
- Ultrasound features of adenomyosis and diagnostic challenges.Journal of ultrasound · 2026Observational
- Robot-Assisted Laparoscopic Versus Open Adenomyomectomy: Comparative Surgical and Reproductive Outcomes.Journal of clinical medicine · 2026Article
- Engineering the Human Endometrial-Embryo Interface: Breakthroughs in 3D Uterine Models.Biomolecules · 2026Review
- Association of Smoking and Alcohol Consumption with Female Reproductive Diseases: A Mendelian Randomization Study on the Mediating Role of Circulating Metabolites.International journal of women's health · 2026Article
- Development and validation of a nomogram to predict symptomatic recurrence following laparoscopic adenomyomectomy.Frontiers in medicine · 2026Article
- NUMB in Endometrial Pathology: From Adenomyosis Expression Patterns to Endometrial Cancer Survival Implications.Current issues in molecular biology · 2025Article
- Article
- Risk factors for uterine adenomyosis diagnosed by MRI in women of reproductive age.Annals of medicine and surgery (2012) · 2025Article
- Sequential therapy of dienogest following relugolix for adenomyosis and impact on symptoms and serum CA125 levels: a case series.BMC women's health · 2025Article
- Endometriosis and adenomyosis research priorities in India and Sri Lanka: a call for regional collaboration.The Lancet regional health. Southeast Asia · 2025Review
- Anti-angiogenic therapy as potential treatment for adenomyosis.Angiogenesis · 2025Article
- How Reproducible Are the Ultrasound Features of Adenomyosis Defined by the Revised MUSA Consensus?Journal of clinical medicine · 2025Article
- Ovarian adenomyoma: a case report.BMC women's health · 2025Article
- Retrospective study of the factors involved in the development of adenomyosis and theMedicine and pharmacy reports · 2024Article
- 'Fish in a Net' and 'Swiss cheese' pattern 2 cases of unusual adenomyosis with different β-HCG level.Radiology case reports · 2024Article
- Comparison of ultra-long gonadotropin releasing hormone agonist versus standard downregulation in women with adenomyosis undergoing frozen-thawed embryo transfer: a randomized clinical trial.Contraception and reproductive medicine · 2024Article
- From Diagnosis to Fertility: Optimizing Treatment of Adenomyosis for Reproductive Health.Journal of clinical medicine · 2024Review
17 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Adenomyosis is an important clinical challenge in gynecology and healthcare economics; in its fully developed form, hysterectomy is often used to treat it in premenopausal and perimenopausal women. Symptoms of adenomyosis typically include menorrhagia, pelvic pain and dysmenorrhea. Moreover, adenomyosis and leiomyomas commonly coexist in the same uterus, and differentiating the symptoms for each pathological process can be problematic. Although it has been recognized for over a century, reliable epidemiological studies on this condition are limited, because only postoperative diagnoses were possible in the past. Minimally invasive surgical techniques (endometrial ablation/resection, myometrial excision/reduction, myometrial electrocoagulation, uterine artery ligation) have had limited success in the treatment of adenomyosis, and the reported data for these procedures have been obtained from case reports or small case series with only short follow-up times. However, newer techniques including uterine artery embolization (UAE) and magnetic resonance imaging guided focused ultrasound (MRgFUS) show promise in treating adenomyosis. The data is strongest for UAE; these studies have the largest patient cohorts. However, none of the UAE studies were randomized or controlled. Thus, despite the clinical importance of adenomyosis, there is little evidence on which to base treatment decisions. The objective of this review is to summarize the epidemiology, risk factors, clinical phenotype and to evaluate the accrued experience with surgical and interventional alternatives to hysterectomy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.