ArticleGeburtshilfe und Frauenheilkunde2013
Breast Cancer Risk - From Genetics to Molecular Understanding of Pathogenesis.
Article in Geburtshilfe und Frauenheilkunde, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed.
- Polymorphisms in the RANK/RANKL genes and their effect on bone specific prognosis in breast cancer patients.BioMed research international · 2014Trial
- Influence of Family History of Breast or Ovarian Cancer on Pathological Complete Response and Long-Term Prognosis in Breast Cancer Patients Treated with Neoadjuvant Chemotherapy.Breast care (Basel, Switzerland) · 2021Article
- Cost effectiveness of bilateral risk-reducing mastectomy and salpingo-oophorectomy.European journal of medical research · 2019Article
- Update Breast Cancer 2018 (Part 3) - Genomics, Individualized Medicine and Immune Therapies - in the Middle of a New Era: Prevention and Treatment Strategies for Early Breast Cancer.Geburtshilfe und Frauenheilkunde · 2018Article
- Prediction of pathological complete response and prognosis in patients with neoadjuvant treatment for triple-negative breast cancer.BMC cancer · 2018Article
- Saliva samples as a source of DNA for high throughput genotyping: an acceptable and sufficient means in improvement of risk estimation throughout mammographic diagnostics.European journal of medical research · 2018Article
- Update Breast Cancer 2018 (Part 2) - Advanced Breast Cancer, Quality of Life and Prevention.Geburtshilfe und Frauenheilkunde · 2018Article
- Correlation of mammographic density and serum calcium levels in patients with primary breast cancer.Cancer medicine · 2017Observational
- Predicting Triple-Negative Breast Cancer Subtype Using Multiple Single Nucleotide Polymorphisms for Breast Cancer Risk and Several Variable Selection Methods.Geburtshilfe und Frauenheilkunde · 2017Article
- Association of the genetic diversity of killer cell immunoglobulin-like receptor genes and HLA-C ligand in Saudi women with breast cancer.Immunogenetics · 2017Article
- Endometriosis as a risk factor for ovarian or endometrial cancer - results of a hospital-based case-control study.BMC cancer · 2015Article
- ICG Fluorescence Technique for the Detection of Sentinel Lymph Nodes in Breast Cancer: Results of a Prospective Open-label Clinical Trial.Geburtshilfe und Frauenheilkunde · 2015Article
- Knowledge and attitudes regarding medical research studies among patients with breast cancer and gynecological diseases.BMC cancer · 2015Article
- Impact of Age, Obesity and Smoking on Patient Satisfaction with Breast Implant Surgery - A Unicentric Analysis of 318 Implant Reconstructions after Mastectomy.Geburtshilfe und Frauenheilkunde · 2015Article
- Hormone Therapy and its Effect on the Prognosis in Breast Cancer Patients.Geburtshilfe und Frauenheilkunde · 2015Article
- Breast Cancer Update 2014 - Focus on the Patient and the Tumour.Geburtshilfe und Frauenheilkunde · 2015Article
- Comparison of Sonography versus Digital Breast Tomosynthesis to Locate Intramammary Marker Clips.Geburtshilfe und Frauenheilkunde · 2015Article
- Biomarkers in Patients with Metastatic Breast Cancer and the PRAEGNANT Study Network.Geburtshilfe und Frauenheilkunde · 2015Article
- Abnormal expression of serum soluble E-cadherin is correlated with clinicopathological features and prognosis of breast cancer.Medical science monitor : international medical journal of experimental and clinical research · 2014Article
- Molecular Markers as Prognostic Factors in DCIS and Small Invasive Breast Cancers.Geburtshilfe und Frauenheilkunde · 2014Article
Corrections and comments
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Authors and funding
17 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Several advancements over the last decade have triggered the developments in the field of breast cancer risk research. One of them is the availability of the human genome sequence along with cheap genotyping possibilities. Another is the globalization of research, which has led to the growth of research collaboration into large international consortia that facilitate the pooling of clinical and genotype data of hundreds of thousands of patients and healthy control individuals. This review concerns with the recent developments in breast cancer risk research and focuses on the discovery of new genetic breast cancer risk factors and their meaning in the context of established non-genetic risk factors. Finally the clinical application is highly dependent on the accuracy of breast cancer risk prediction models, not only for all breast cancer patients, but also for molecular subtypes, preferably for those which are associated with an unfavorable prognosis. Recently risk prediction incorporates all possible risk factors, which include epidemiological risk factors, mammographic density and genetic risk factors.
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