Evidence map›Paper›PMID 24771327›Full record

ArticleChembiochem : a European journal of chemical biology2014

Crystal structures of acyl carrier protein in complex with two catalytic partners show a dynamic role in cellular metabolism.

Sean A Newmister, David H Sherman

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chembiochem : a European journal of chemical biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sean A NewmisterLife Sciences Institute, University of Michigan, 210 Washtenaw Avenue, Ann Arbor, MI 48109 (USA).
David H Sherman

Funding

Molecular Analysis of Modular Polyketide SynthasesR01GM076477 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SHERMAN, DAVID H, SMITH, JANET L. · 2006 to 2018
$5.2M
NIGMS NIH HHS GM076477NIGMS NIH HHS R01 GM076477
6 · The paper itself

Abstract

ACP captured in action: Two recently reported crystal structures are the first to capture ACP-mediated substrate delivery to a catalytic partner at high resolution. These studies highlight key interactions of transient ACP-partner complexes and define the dynamic movements of ACP that facilitate substrate delivery and trigger complex dissociation.

Indexed as

Acyl Carrier ProteinAcyltransferasesBiocatalysisCrystallography, X-RayEscherichia coliEscherichia coli ProteinsFatty Acid Synthase, Type IIHydro-LyasesModels, MolecularProtein Binding3-hydroxyacyl-(acyl-carrier-protein) dehydrataseacpP protein, E coliacyl-(acyl-carrier-protein)-UDP-N-acetylglucosamine acyltransferaseAcyl Carrier ProteinAcyltransferasesEscherichia coli ProteinsFatty Acid Synthase, Type IIHydro-Lyasesacyl carrier proteinsbiosynthesisfatty acidslipid A

Identifiers

PMID24771327
PMCPMC4122295

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.