ArticlePediatric radiology2014
Gadobenate-dimeglumine-enhanced magnetic resonance imaging for hepatic lesions in children.
Article in Pediatric radiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 18 citations in OpenAlex.
- Liver magnetic resonance imaging: how we do it.Pediatric radiology · 2022Review
- Pedunculated hepatic focal nodular hyperplasia: A case report and review of the literature.Clinical case reports · 2021Article
- Intravenous gadolinium-based hepatocyte-specific contrast agents (HSCAs) for contrast-enhanced liver magnetic resonance imaging in pediatric patients: what the radiologist should know.Pediatric radiology · 2019Review
- Hepatocyte-specific contrast media: not so simple.Pediatric radiology · 2018Review
- Magnetic resonance imaging features of common focal liver lesions in children.Pediatric radiology · 2018Review
- Pedunculated focal nodular hyperplasia in a healthy toddler.Proceedings (Baylor University. Medical Center) · 2018Article
- Can diffusion-weighted imaging distinguish between benign and malignant pediatric liver tumors?Pediatric radiology · 2018Article
- Imaging of late complications of cancer therapy in children.Pediatric radiology · 2017Review
- MRI of paediatric liver tumours: How we review and report.Cancer imaging : the official publication of the International Cancer Imaging Society · 2016Review
- Pediatric multifocal liver lesions evaluated by MRI.The Indian journal of radiology & imagingArticle
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Authors and funding
4 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMagnetic resonance imaging enhanced by hepatocyte-specific contrast media has been found useful to characterize liver lesions in adults and children.
objectiveTo present our experience with gadobenate dimeglumine (Gd-BOPTA)-enhanced MRI for evaluation of focal liver lesions in children. MATERIALS AND
methodsWe retrospectively reviewed gadobenate-dimeglumine-enhanced MR images obtained for evaluation of suspected hepatic lesions in 30 children. Signal characteristics on various sequences including 45- to 60-min hepatobiliary phase images were noted by two radiologists. Chart review identified relevant clinical details including history of cancer treatment, available pathology and stability of lesion size on follow-up imaging.
resultsOf the 30 children who had gadobenate-enhanced MRI, 26 showed focal lesions. Diagnoses in 26 children were focal nodular hyperplasia (FNH) in 15, hemangiomas in 3, regenerating nodules in 3, focal fatty infiltration in 2, indeterminate lesions in 3, and one patient each with adenomas, hepatoblastoma and metastasis. Two patients had multiple diagnoses. All FNH lesions (39), all regenerative nodules (19) and an indeterminate lesion were iso- or hyperintense on hepatobiliary-phase images while all other lesions (28) were hypointense to hepatic parenchyma. The average follow-up period was 21.7 months.
conclusionOur experience with gadobenate-enhanced MRI indicates potential utility of gadobenate in the evaluation of pediatric hepatic lesions in differentiating FNH and regenerating nodules from other lesions.
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