ArticleMolecular biology and evolution2014
Accelerated evolution of morph-biased genes in pea aphids.
Article in Molecular biology and evolution, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed, 48 citations in OpenAlex.
- New annotations for three pea aphid genome assemblies allow comparative analyses of duplication and gene family evolution.G3 (Bethesda, Md.) · 2026Article
- Multi-Omic Analysis Reveals Population Differentiation and Signatures of Social Evolution in Tetragonula Stingless Bees.Molecular ecology · 2025Article
- Genetic regulators of a resource polyphenism interact to couple predatory morphology and behaviour.Proceedings. Biological sciences · 2024Article
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- Phylloxera and Aphids Show Distinct Features of Genome Evolution Despite Similar Reproductive Modes.Molecular biology and evolution · 2023Article
- Pea aphid winged and wingless males exhibit reproductive, gene expression, and lipid metabolism differences.Current research in insect science · 2022Article
- Transitions to asexuality and evolution of gene expression inProceedings. Biological sciences · 2021Article
- Male-Biased microRNA Discovery in the Pea Aphid.Insects · 2021Article
- Chromosome-Scale Genome Assemblies of Aphids Reveal Extensively Rearranged Autosomes and Long-Term Conservation of the X Chromosome.Molecular biology and evolution · 2021Article
- The Aphid X Chromosome Is a Dangerous Place for Functionally Important Genes: Diverse Evolution of Hemipteran Genomes Based on Chromosome-Level Assemblies.Molecular biology and evolution · 2020Article
- Gene Expression Profiling Indicated Diverse Functions and Characteristics of Core Genes in Pea Aphid.Insects · 2020Article
- RNA-Seq-Based Whole Transcriptome Analysis of IPEC-J2 Cells During Swine Acute Diarrhea Syndrome Coronavirus Infection.Frontiers in veterinary science · 2020Article
- Core transcriptional signatures of phase change in the migratory locust.Protein & cell · 2019Article
- Article
- Sex-specific changes in the aphid DNA methylation landscape.Molecular ecology · 2019Article
- Differential wing polyphenism adaptation across life stages under extreme high temperatures in corn leaf aphid.Scientific reports · 2019Article
- A Laterally Transferred Viral Gene Modifies Aphid Wing Plasticity.Current biology : CB · 2019Article
- Comparative Genomics Reveals Accelerated Evolution of Fright Reaction Genes in Ostariophysan Fishes.Frontiers in genetics · 2019Article
- Chemical Ecology and Sociality in Aphids: Opportunities and Directions.Journal of chemical ecology · 2018Review
- Extensive Differential Splicing Underlies Phenotypically Plastic Aphid Morphs.Molecular biology and evolution · 2018Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
Phenotypic plasticity, the production of alternative phenotypes (or morphs) from the same genotype due to environmental factors, results in some genes being expressed in a morph-biased manner. Theoretically, these morph-biased genes experience relaxed selection, the consequence of which is the buildup of slightly deleterious mutations at these genes. Over time, this is expected to result in increased protein divergence at these genes between species and a signature of relaxed purifying selection within species. Here we test these theoretical expectations using morph-biased genes in the pea aphid, a species that produces multiple morphs via polyphenism. We find that morph-biased genes exhibit faster rates of evolution (in terms of dN/dS) relative to unbiased genes and that divergence generally increases with increasing morph bias. Further, genes with expression biased toward rarer morphs (sexual females and males) show faster rates of evolution than genes expressed in the more common morph (asexual females), demonstrating that the amount of time a gene spends being expressed in a morph is associated with its rate of evolution. And finally, we show that genes expressed in the rarer morphs experience decreased purifying selection relative to unbiased genes, suggesting that it is a relaxation of purifying selection that contributes to their faster rates of evolution. Our results provide an important empirical look at the impact of phenotypic plasticity on gene evolution.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.