ArticleRevista Brasileira de terapia intensiva
[Predictors of extubation failure and reintubation in newborn infants subjected to mechanical ventilation].
Article in Revista Brasileira de terapia intensiva. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- [Clinical efficacy of nasal high-frequency ventilation in treatment of neonatal respiratory distress syndrome: a Meta analysis].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2018Pooled it
- Markers of Successful Extubation in Extremely Preterm Infants, and Morbidity After Failed Extubation.The Journal of pediatrics · 2017Trial
- Weight-adjusted rapid shallow breathing index during spontaneous breathing trial in mechanically ventilated preterm infants.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Nomogram-based prediction model for extubation failure in preterm infants with invasive mechanical ventilation.Italian journal of pediatrics · 2025Article
- Using machine-learning models to predict extubation failure in neonates with bronchopulmonary dysplasia.BMC pulmonary medicine · 2024Article
- Predictive factors for extubation success in very low and extremely low birth weight preterm infants.Canadian journal of respiratory therapy : CJRT = Revue canadienne de la therapie respiratoire : RCTR · 2023Article
- Effectiveness and safety of early versus late caffeine therapy in managing apnoea of prematurity among preterm infants: a retrospective cohort study.International journal of clinical pharmacy · 2022Article
- Risk Factors of Extubation Failure in Intubated Preterm Infants at a Tertiary Care Hospital in Oman.Sultan Qaboos University medical journal · 2022Article
- Use of Dexamethasone to Prevent Extubation Failure in Pediatric Intensive Care Unit: A Randomized Controlled Clinical Trial.Journal of pediatric intensive care · 2022Article
- The Application of Pulmonary Ultrasound in Neonatal Ventilator-Associated Pneumonia.Frontiers in pediatrics · 2022Article
- Reintubation rates after extubation to different non-invasive ventilation modes in preterm infants.BMC pediatrics · 2021Article
- Effects of an extubation readiness test protocol at a tertiary care fully outborn neonatal intensive care unit.Canadian journal of respiratory therapy : CJRT = Revue canadienne de la therapie respiratoire : RCTR · 2019Article
- Predictors of extubation outcomes among extremely and very preterm infants: a retrospective cohort study.Jornal de pediatriaArticle
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo identify risk factors for extubation failure and reintubation in newborn infants subjected to mechanical ventilation and to establish whether ventilation parameters and blood gas analysis behave as predictors of those outcomes.
methodsProspective study conducted at a neonatal intensive care unit from May to November 2011. A total of 176 infants of both genders subjected to mechanical ventilation were assessed after extubation. Extubation failure was defined as the need to resume mechanical ventilation within less than 72 hours. Reintubation was defined as the need to reintubate the infants any time after the first 72 hours.
resultsBased on the univariate analysis, the variables gestational age <28 weeks, birth weight <1,000 g and low Apgar scores were associated with extubation failure and reintubation. Based on the multivariate analysis, the variables length of mechanical ventilation (days), potential of hydrogen (pH) and partial pressure of oxygen (pO₂) remained associated with extubation failure, and the five-minute Apgar score and age at extubation were associated with reintubation.
conclusionLow five-minute Apgar scores, age at extubation, length of mechanical ventilation, acid-base disorders and hyperoxia exhibited associations with the investigated outcomes of extubation failure and reintubation.
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