Evidence map›Paper›PMID 24769378›Full record

ReviewClinical immunology (Orlando, Fla.)2014

Plasmacytoid dendritic cells of the gut: relevance to immunity and pathology.

Vincent C Lombardi, Svetlana F Khaiboullina

Open access · hybridAbstract readReview
In one paragraph

Review in Clinical immunology (Orlando, Fla.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Gut Innate Immunity and HIV Pathogenesis.Current HIV/AIDS reports · 2021
    Review
  11. Review
  12. Gut Microbiota, the Immune System, and Cytotoxic T Lymphocytes.Methods in molecular biology (Clifton, N.J.) · 2021
    Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Vincent C LombardiDepartment of Biochemistry and Molecular Biology, University of Nevada School of Medicine, WPI, University of Nevada, Reno, 1664 N Virginia St. MS 0552, Reno, NV 89557, USA. Electronic address: vlombardi@medicine.nevada.edu.
Svetlana F KhaiboullinaDepartment of Biochemistry and Molecular Biology, University of Nevada School of Medicine, WPI, University of Nevada, Reno, 1664 N Virginia St. MS 0552, Reno, NV 89557, USA; Institute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, Russia. Electronic address: svkhaiboullina@gmail.com.
Kazan Federal University · RUUniversity of Nevada, Reno · US

Funding

New Strategies to Decipher the Pathophysiology of Chronic Fatigue SyndromeR01AI078234 · NIAID · NEVADA CENTER FOR BIOMEDICAL RESEARCH · PI LOMBARDI, VINCENT C · 2009 to 2013
$1.5M
NIAID NIH HHS AI078234NIAID NIH HHS R01 AI078234
6 · The paper itself

Abstract

Plasmacytoid dendritic cells (pDCs) are bone marrow-derived immune cells with the ability to express copious amounts of type I and III interferon (IFN) and can differentiate into antigen-presenting dendritic cells as a result of stimulation by pathogen-derived nucleic acid. These powerful combined functionalities allow pDCs to bridge the innate and adaptive immune systems resulting in a concerted pathogen response. The contribution of pDCs to gastrointestinal immunity is only now being elucidated and is proving to be a critical component in systemic immunity. This review will explore the immunology of pDCs and will discuss their involvement in human disease and tolerance with an emphasis on those in the gastrointestinal lymphoid tissue.

Indexed as

Adaptive ImmunityAnimalsAntigen PresentationAutoimmune DiseasesCytokinesDendritic CellsGastrointestinal TractHumansPeyer's PatchesToll-Like ReceptorsCytokinesToll-Like ReceptorsAutoimmunityGALT;Gut;Interferon;pDC;Tolerance;

Identifiers

PMID24769378
PMCPMC4063559
OpenAlexW1977437842

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.