Evidence map›Paper›PMID 24769313›Full record

ArticleCryobiology2014

Thermal expansion of vitrified blood vessels permeated with DP6 and synthetic ice modulators.

David P Eisenberg, Michael J Taylor, Jorge L Jimenez-Rios, Yoed Rabin

Abstract read
In one paragraph

Article in Cryobiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. New Approaches to Cryopreservation of Cells, Tissues, and Organs.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2019
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

David P EisenbergBiothermal Technology Laboratory, Department of Mechanical Engineering, Carnegie Mellon University, Pittsburgh, PA 15213, United States.
Michael J TaylorBiothermal Technology Laboratory, Department of Mechanical Engineering, Carnegie Mellon University, Pittsburgh, PA 15213, United States; Cell and Tissue Systems, Inc., 2231 Technical Parkway, N. Charleston, SC 29406, United States.
Jorge L Jimenez-RiosBiothermal Technology Laboratory, Department of Mechanical Engineering, Carnegie Mellon University, Pittsburgh, PA 15213, United States.
Yoed RabinBiothermal Technology Laboratory, Department of Mechanical Engineering, Carnegie Mellon University, Pittsburgh, PA 15213, United States. Electronic address: rabin@cmu.edu.

Funding

Thermal Expansion of Cryoprotective Agents Combined with Synthetic Ice BlockersR21EB011751 · NIBIB · CARNEGIE-MELLON UNIVERSITY · PI RABIN, YOED · 2010 to 2011
$390k
NIBIB NIH HHS R21 EB011751NIBIB NIH HHS R21EB011751
6 · The paper itself

Abstract

This study provides thermal expansion data for blood vessels permeated with the cryoprotective cocktail DP6, when combined with selected synthetic ice modulators (SIMs): 12% polyethylene glycol 400, 6% 1,3-cyclohexanediol, and 6% 2,3-butanediol. The general classification of SIMs includes molecules that modulate ice nucleation and growth, or possess properties of stabilizing the amorphous state, by virtue of their chemical structure and at concentrations that are not explained on a purely colligative basis. The current study is part of an ongoing effort to characterize thermo-mechanical effects on structural integrity of cryopreserved materials, where thermal expansion is the driving mechanism to thermo-mechanical stress. This study focuses on the lower part of the cryogenic temperature range, where the cryoprotective agent (CPA) behaves as a solid for all practical applications. By combining results obtained in the current study with literature data on the thermal expansion in the upper part of the cryogenic temperature range, unified thermal expansion curves are presented.

Indexed as

VitrificationAnimalsBlood VesselsButylene GlycolsCryopreservationCryoprotective AgentsCyclohexanolsEquipment DesignGoatsIcePermeabilityPolyethylene GlycolsStress, MechanicalTemperature2,3-butylene glycolButylene GlycolsCryoprotective Agentscyclohexane-1,3-diolCyclohexanolsIcePolyethylene GlycolsCryopreservationSolid mechanicsSynthetic ice modulatorsThermal expansionThermal stressVitrification

Identifiers

PMID24769313
PMCPMC4359760

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.