ReviewPhysiology & behavior2014
A functional neuroimaging review of obesity, appetitive hormones and ingestive behavior.
Review in Physiology & behavior, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed, 108 citations in OpenAlex.
- Effects of Dapagliflozin and Combination Therapy With Exenatide on Food-Cue Induced Brain Activation in Patients With Type 2 Diabetes.The Journal of clinical endocrinology and metabolism · 2022Trial
- Neuroimaging of hypothalamic mechanisms related to glucose metabolism in anorexia nervosa and obesity.The Journal of clinical investigation · 2020Trial
- Trial
- Using neuroimaging to investigate the impact of Mandolean® training in young people with obesity: a pilot randomised controlled trial.BMC pediatrics · 2018Trial
- Trial
- Less-than-expected weight loss in normal-weight women undergoing caloric restriction and exercise is accompanied by preservation of fat-free mass and metabolic adaptations.European journal of clinical nutrition · 2017Trial
- Effect of extended morning fasting upon ad libitum lunch intake and associated metabolic and hormonal responses in obese adults.International journal of obesity (2005) · 2016Trial
- Trial
- Patterns of change in impulsivity after bariatric surgery: evidence from 24 months of follow-up.BMC surgery · 2026Article
- The Role of L-Glutamate as an Umami Substance for the Reduction of Salt Consumption: Lessons from Clinical Trials.Nutrients · 2025Review
- Applying psycho-behavioural phenotyping in obesity characterization.Reviews in endocrine & metabolic disorders · 2023Review
- Higher body weight-dependent neural activation during reward processing.Brain imaging and behavior · 2023Article
- Food reinforcement architecture: A framework for impulsive and compulsive overeating and food abuse.Obesity (Silver Spring, Md.) · 2023Review
- Sex Differences in Effects of Mood, Eating-Related Behaviors, and BMI on Food Appeal and Desire to Eat: A Cross-Sectional Survey Study.Nutrients · 2023Article
- Obesity and brain structure in schizophrenia - ENIGMA study in 3021 individuals.Molecular psychiatry · 2022Article
- Changes in Food Choice, Taste, Desire, and Enjoyment 1 Year after Sleeve Gastrectomy: A Prospective Study.Nutrients · 2022Article
- Role of diet and its effects on the gut microbiome in the pathophysiology of mental disorders.Translational psychiatry · 2022Review
- Homeostasis and food craving in obesity: a functional MRI study.International journal of obesity (2005) · 2021Article
- Multimodal brain predictors of current weight and weight gain in children enrolled in the ABCD study ®.Developmental cognitive neuroscience · 2021Article
- Child neurobiology impacts success in family-based behavioral treatment for children with obesity.International journal of obesity (2005) · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Adequate energy intake is vital for the survival of humans and is regulated by complex homeostatic and hedonic mechanisms. Supported by functional MRI (fMRI) studies that consistently demonstrate differences in brain response as a function of weight status during exposure to appetizing food stimuli, it has been posited that hedonically driven food intake contributes to weight gain and obesity maintenance. These food reward theories of obesity are reliant on the notion that the aberrant brain response to food stimuli relates directly to ingestive behavior, specifically, excess food intake. Importantly, functioning of homeostatic neuroendocrine regulators of food intake, such as leptin and ghrelin, are impacted by weight status. Thus, data from studies that evaluate the effect on weight status on brain response to food may be a result of differences in neuroendocrine functioning and/or behavior. In the present review, we examine the influence of weight and weight change, exogenous administration of appetitive hormones, and ingestive behavior on BOLD response to food stimuli.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.