Evidence map›Paper›PMID 24768951›Full record

ReviewInternational journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience2014

Perinatal biomarkers in prematurity: early identification of neurologic injury.

Maria Andrikopoulou, Ahmad Almalki, Azadeh Farzin, Christina N Cordeiro, Michael V Johnston, Irina Burd

Open access · greenAbstract readReview
In one paragraph

Review in International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. A predictive clinical model for moderate to severe intraventricular hemorrhage in very low birth weight infants.Journal of perinatology : official journal of the California Perinatal Association · 2022
    Observational
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Maria AndrikopoulouIntegrated Research Center for Fetal Medicine, Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Ahmad AlmalkiIntegrated Research Center for Fetal Medicine, Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Azadeh FarzinDivision of Neonatology, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Christina N CordeiroIntegrated Research Center for Fetal Medicine, Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Michael V JohnstonDepartment of Neuroscience, Kennedy Krieger Institute, Baltimore, MD, United States.
Irina BurdIntegrated Research Center for Fetal Medicine, Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD, United States; Department of Neuroscience, Kennedy Krieger Institute, Baltimore, MD, United States; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, United States. Electronic address: iburd@jhmi.edu.
Johns Hopkins University · USKennedy Krieger Institute · USJohns Hopkins Medicine · US

Funding

MR Microimaging of Mouse Brain DevelopmentR01EB003543 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI MORI, SUSUMU · 2004 to 2012
$4.5M
NEUROTRANSMITTER INJURY MECHANISMS IN DEVELOPING BRAINR01NS028208 · NINDS · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI JOHNSTON, MICHAEL VAN DOREN · 1990 to 2011
$3.4M
IL-1beta regulation of perinatal brain injuryK08HD073315 · NICHD · JOHNS HOPKINS UNIVERSITY · PI BURD, IRINA · 2012 to 2016
$684k
NIBIB NIH HHS R01 EB003543NICHD NIH HHS K08 HD073315NINDS NIH HHS R01 NS028208PHS HHS NICHDK08HD073315PHS HHS NINDSNS28208
6 · The paper itself

Abstract

Over the past few decades, biomarkers have become increasingly utilized as non-invasive tools in the early diagnosis and management of various clinical conditions. In perinatal medicine, the improved survival of extremely premature infants who are at high risk for adverse neurologic outcomes has increased the demand for the discovery of biomarkers in detecting and predicting the prognosis of infants with neonatal brain injury. By enabling the clinician to recognize potential brain damage early, biomarkers could allow clinicians to intervene at the early stages of disease, and to monitor the efficacy of those interventions. This review will first examine the potential perinatal biomarkers for neurologic complications of prematurity, specifically, intraventricular hemorrhage (IVH), periventricular leukomalacia (PVL) and posthemorrhagic hydrocephalus (PHH). It will also evaluate knowledge gained from animal models regarding the pathogenesis of perinatal brain injury in prematurity.

Indexed as

Early DiagnosisNervous System DiseasesAnimalsBiomarkersFemaleHumansInfant, PrematureMalePregnancyBiomarkersBiomarkersBrain injuryIntraventricular hemorrhagePeriventricular leukomalaciaPrematurity

Identifiers

PMID24768951
PMCPMC4101019
OpenAlexW2068960000

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.