Evidence map›Paper›PMID 24768917›Full record

ArticlePreventive medicine2014

Physical inactivity and long-term rates of community-acquired sepsis.

Henry E Wang, John Baddley, Russell L Griffin, Suzanne Judd, George Howard, John P Donnelly, Monika M Safford

Abstract read
In one paragraph

Article in Preventive medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Henry E WangDepartment of Emergency Medicine, University of Alabama School of Medicine, USA. Electronic address: hwang@uabmc.edu.
John BaddleyDivision of Infectious Diseases, Department of Medicine, University of Alabama School of Medicine, USA.
Russell L GriffinDepartment of Epidemiology, School of Public Health, University of Alabama at Birmingham, USA.
Suzanne JuddDepartment of Biostatistics, School of Public Health, University of Alabama at Birmingham, USA.
George HowardDepartment of Biostatistics, School of Public Health, University of Alabama at Birmingham, USA.
John P DonnellyDepartment of Epidemiology, School of Public Health, University of Alabama at Birmingham, USA.
Monika M SaffordDivision of Preventive Medicine, Department of Medicine, University of Alabama School of Medicine, USA.

Funding

VCID and Stroke in a Bi-racial National CohortU01NS041588 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CUSHMAN, MARY, HOWARD, GEORGE · 2002 to 2022
$96.0M
UAB CENTER FOR CLINICAL AND TRANSLATIONAL SCIENCE (CCTS) UL1: BPCAUL1RR025777 · NCRR · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GUAY-WOODFORD, LISA MARIE · 2008 to 2011
$22.3M
University of Alabama at Birmingham's Diabetes Research CenterP30DK079626 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Kirk Michael Habegger · 2013 to 2026
$19.5M
Understanding Obesity In Relation to the Built EnvironmentP20MD006899 · NIMHD · JACKSON STATE UNIVERSITY · PI ANTOINE-LAVIGNE, DONNA A · 2012 to 2016
$5.3M
Risk Factors for Sepsis in the CommunityR01NR012726 · NINR · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI WANG, HENRY E. · 2011 to 2015
$2.6M
NCRR NIH HHS UL1 RR025777NCRR NIH HHS UL1-RR025777NIDDK NIH HHS P30 DK079626NIMHD NIH HHS P20 MD006899NINDS NIH HHS U01 NS041588NINDS NIH HHS U01-NS041588NINR NIH HHS R01 NR012726NINR NIH HHS R01-NR012726
6 · The paper itself

Abstract

objectiveThe authors sought to determine the association between physical inactivity (characterized by exercise and television watching levels) and long-term rates of community-acquired sepsis.

methodsThe study utilized a population-based cohort of 30,183 adult (≥45 years) community dwelling adults. Subjects reported weekly exercise (low=none, medium=1-3times/week, high=≥4times/week) and daily television watching (low=<1h/day, medium=1-3h/day, high=≥4h/day) levels. The authors evaluated the association between exercise, television watching and rates of sepsis, defined as hospital treatment for a serious infection with ≥2 Systemic Inflammatory Response Syndrome (SIRS) criteria.

resultsAmong 30,183 participants, 1500 experienced a sepsis event. Reported weekly exercise was: high 8798 (29.2%), medium 10,695 (35.4%), and low 10,240 (33.9%). Where available, reported daily television watching was: low 4615 (19.6%), medium 11,587 (49.3%) and high 7317 (31.1%). Decreased weekly exercise was associated with increased adjusted sepsis rates (high - referent; medium - HR 1.02, 95% CI 0.96-1.20; low - 1.33, 1.13-1.56). Daily television watching was not associated with sepsis rates. Sepsis rates were highest among those with both low exercise and high television watching levels (HR 1.49, 95% CI: 1.10-2.01).

conclusionsPhysical inactivity may be associated with increased long-term rates of community-acquired sepsis.

Indexed as

Sedentary BehaviorAgedAged, 80 and overCohort StudiesCommunity-Acquired InfectionsFemaleHumansImmune SystemMaleMiddle AgedMotor ActivityPopulation SurveillanceSepsisUnited StatesDietEpidemiologyExerciseInfectionsPhysical activitySedentary behaviorSepsis

Identifiers

PMID24768917
PMCPMC4101049

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.