Evidence map›Paper›PMID 24768686›Full record

ReviewTranslational research : the journal of laboratory and clinical medicine2015

RNA epigenetics.

Nian Liu, Tao Pan

Abstract readReview
In one paragraph

Review in Translational research : the journal of laboratory and clinical medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Functional Consequences Paternal Preconceptual Alcohol Consumption.Current topics in behavioral neurosciences · 2025
    Review
  5. Unveiling the dynamics and therapeutic potential of mInternational journal of biological sciences · 2025
    Review
  6. Article
  7. Review
  8. Review
  9. Pulling the trigger: Noncoding RNAs in white adipose tissue browning.Reviews in endocrine & metabolic disorders · 2024
    Review
  10. Review
  11. BMP9-ID1 Pathway Attenuates NInternational journal of molecular sciences · 2024
    Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Review
  20. Review

13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Nian LiuDepartment of Chemistry, University of Chicago, Chicago, Ill.
Tao PanDepartment of Biochemistry and Molecular Biology, University of Chicago, Chicago, Ill; Institute of Biophysical Dynamics, University of Chicago, Chicago, Ill. Electronic address: taopan@uchicago.edu.

Funding

Re-Engineering Translational Research at the University of ChicagoUL1TR000430 · NCATS · UNIVERSITY OF CHICAGO · PI SOLWAY, JULIAN · 2012 to 2016
$20.2M
Discovering the epigenetics of RNA modificationsR01GM088599 · NIGMS · UNIVERSITY OF CHICAGO · PI HE, CHUAN, PAN, TAO · 2009 to 2012
$1.2M
NCATS NIH HHS UL1 TR000430NIGMS NIH HHS GM88599NIGMS NIH HHS R01 GM088599
6 · The paper itself

Abstract

Mammalian messenger RNA (mRNA) and long noncoding RNA (lncRNA) contain tens of thousands of posttranscriptional chemical modifications. Among these, the N(6)-methyl-adenosine (m(6)A) modification is the most abundant and can be removed by specific mammalian enzymes. m(6)A modification is recognized by families of RNA binding proteins that affect many aspects of mRNA function. mRNA/lncRNA modification represents another layer of epigenetic regulation of gene expression, analogous to DNA methylation and histone modification.

Indexed as

Epigenesis, GeneticAdenosineAnimalsHumansMethyltransferasesMiceRNARNA-Binding ProteinsRNA, Long NoncodingRNA, MessengerTranslational Research, BiomedicalAdenosineMethyltransferasesN-methyladenosineRNARNA-Binding ProteinsRNA, Long NoncodingRNA, Messenger

Identifiers

PMID24768686
PMCPMC4190089

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.