Evidence map›Paper›PMID 24768534›Full record

Observational studyJournal of critical care2014

Functional electrical stimulation with cycling in the critically ill: a pilot case-matched control study.

Selina M Parry, Sue Berney, Stephen Warrillow, Doa El-Ansary, Adam L Bryant, Nicholas Hart, Zudin Puthucheary, Renè Koopman, Linda Denehy

4 registry-linked trialsOpen access · greenAbstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Journal of critical care, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 34 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 3 pooled it
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02214823 nacompletednot on this map

Functional Electrical Stimulation Assisted Cycling (eStimCycle):A Novel Intervention to Improve Outcomes in the Critically Ill

TypeinterventionalSponsorAssociate Professor Sue Berney PhD, BPTRan2012 to 2018Enrolled162ConditionsIntensive Care Unit Acquired Weakness (ICUAW)ArmsFES-Cycling, Standard Care
NCT02864745 naunknown statusnot on this mapstarted 2016, after this paper: background citation

Functional Electrical Stimulation-assisted Cycle Ergometry in Critically Ill: Linking Deranged Muscle Physiology to Long-term Functional Outcome

TypeinterventionalSponsorCharles University, Czech RepublicRan2016 to 2020Enrolled150ConditionsCritical IllnessArmsfunctional electrical stimulation-assisted cycle ergometry, standard rehabilitation
NCT02963558 nacompletednot on this mapstarted 2017, after this paper: background citation

ASPIRE: A Study Promoting Critical Illness Recovery in the Elderly

TypeinterventionalSponsorWake Forest University Health SciencesRan2017 to 2021Enrolled24ConditionsAcute Respiratory Distress Syndrome, Critical Illness, Critical CareArmscycle ergometry
NCT03779126 naunknown statusnot on this mapstarted 2018, after this paper: background citation

Efficacy of Combined Low- and High- Frequency Stimulation in Peripheral Muscle Function During Hemodialysis

TypeinterventionalSponsorHospital Sirio-LibanesRan2018 to 2025Enrolled56ConditionsChronic Kidney DiseasesArmsElectrical stimulation
3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 3 syntheses or guidelines pooled it, 92 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Selina M ParryDepartment of Physiotherapy, School of Health Sciences, The University of Melbourne, Melbourne, Australia.
Sue BerneyDepartment of Physiotherapy, Austin Health, Melbourne, Australia.
Stephen WarrillowDepartment of Intensive Care, Austin Health, Melbourne, Australia.
Doa El-AnsaryDepartment of Physiotherapy, School of Health Sciences, The University of Melbourne, Melbourne, Australia.
Adam L BryantDepartment of Physiotherapy, School of Health Sciences, The University of Melbourne, Melbourne, Australia.
Nicholas HartGuy's and St Thomas' NHS Foundation Trust and King's College London, NIHR Comprehensive Biomedical Research Centre, London, UK.
Zudin PuthuchearyDepartment of Asthma, Allergy and Lung Biology, Institute of Health and Human Performance, University College London, Kings College London, London, UK.
Renè KoopmanDepartment of Physiology, The University of Melbourne, Melbourne, Australia.
Linda DenehyDepartment of Physiotherapy, School of Health Sciences, The University of Melbourne, Melbourne, Australia. Electronic address: l.denehy@unimelb.edu.au.
University of Melbourne · AUAustin Health · AUGuy's and St Thomas' NHS Foundation Trust · GBUniversity College London · GB

Funding

Department of Health DRF-2010-03-114
6 · The paper itself

Abstract

purposeThe purpose was to determine (a) safety and feasibility of functional electrical stimulation (FES)-cycling and (b) compare FES-cycling to case-matched controls in terms of functional recovery and delirium outcomes. MATERIALS AND

methodsSixteen adult intensive care unit patients with sepsis ventilated for more than 48 hours and in the intensive care unit for at least 4 days were included. Eight subjects underwent FES-cycling in addition to usual care and were compared to 8 case-matched control individuals. Primary outcomes were safety and feasibility of FES-cycling. Secondary outcomes were Physical Function in Intensive Care Test scored on awakening, time to reach functional milestones, and incidence and duration of delirium.

resultsOne minor adverse event was recorded. Sixty-nine out of total possible 95 FES sessions (73%) were completed. A visible or palpable contraction was present 80% of the time. There was an improvement in Physical Function in Intensive Care Test score of 3.9/10 points in the intervention cohort with faster recovery of functional milestones. There was also a shorter duration of delirium in the intervention cohort.

conclusionsThe delivery of FES-cycling is both safe and feasible. The preliminary findings suggest that FES-cycling may improve function and reduce delirium. Further research is required to confirm the findings of this study and evaluate the efficacy of FES-cycling.

Indexed as

AdultAgedCase-Control StudiesCritical CareCritical IllnessDeliriumElectric Stimulation TherapyFeasibility StudiesFemaleHumansMaleMiddle AgedPilot ProjectsRecovery of FunctionSepsisElectric stimulation therapyIntensive careMuscle weaknessRecovery of functionRehabilitation

Identifiers

PMID24768534
OpenAlexW2024770879

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.