Evidence map›Paper›PMID 24768161›Full record

Trial reportThe Journal of adolescent health : official publication of the Society for Adolescent Medicine2014

Prenatal drug exposure, behavioral problems, and drug experimentation among African-American urban adolescents.

Yan Wang, Stacy Buckingham-Howes, Prasanna Nair, Shijun Zhu, Laurence S Magder, Maureen M Black

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.0field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Risk and protective factors forAddictive behaviors reports · 2020
    Article
  4. Article
  5. Prenatal Drug Exposure and Adolescent Cortisol Reactivity: Association with Behavioral Concerns.Journal of developmental and behavioral pediatrics : JDBP · 2016
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yan WangDepartment of Pediatrics, University of Maryland School of Medicine, Baltimore, Maryland.
Stacy Buckingham-HowesDepartment of Pediatrics, University of Maryland School of Medicine, Baltimore, Maryland.
Prasanna NairDepartment of Pediatrics, University of Maryland School of Medicine, Baltimore, Maryland.
Shijun ZhuOffice of Research, University of Maryland School of Nursing, Baltimore, Maryland.
Laurence S MagderDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland.
Maureen M BlackDepartment of Pediatrics, University of Maryland School of Medicine, Baltimore, Maryland. Electronic address: mblack@peds.umaryland.edu.
University of Maryland, Baltimore · US

Funding

Prenatal Drug Exposure: Effects on Adolescent Brain and Behavioral DevelopmentR01DA021059 · NIDA · UNIVERSITY OF MARYLAND BALTIMORE · PI BLACK, MAUREEN M · 2005 to 2009
$3.1M
PROGRAM FOR DRUG ABUSING WOMEN AND THEIR CHILDRENR01DA007432 · NIDA · UNIVERSITY OF MARYLAND BALTIMORE · PI NAIR, PRASANNA · 1991 to 2002
$867k
NIDA NIH HHS R01 DA007432NIDA NIH HHS R01 DA021059NIDA NIH HHS R01-DA021059NIDA NIH HHS R01-DA07432
6 · The paper itself

Abstract

purposeTo examine how prenatal drug exposure (PDE) to heroin/cocaine and behavioral problems relate to adolescent drug experimentation.

methodsThe sample included African-American adolescents (mean age = 14.2 years, SD = 1.2) with PDE (n = 73) and a nonexposed community comparison (n = 61). PDE status was determined at delivery through toxicology analysis and maternal report. Internalizing/externalizing problems were assessed during adolescence with the Behavior Assessment System for Children, Second Edition. Drug experimentation was assessed by adolescent report and urine analysis. Logistic regression evaluated the likelihood of drug experimentation related to PDE and behavioral problems, adjusting for age, gender, PDE, perceived peer drug use, and caregiver drug use. Interaction terms examined gender modification.

resultsSixty-seven subjects (50%) used drugs: 25 (19%) used tobacco/alcohol only and 42 (31%) used marijuana/illegal drugs. Ninety-four subjects (70%) perceived peer drug use. PDE significantly increased the risk of tobacco/alcohol experimentation (odds ratio = 3.07, 95% confidence interval [CI] 1.09-8.66, p = .034) but not after covariate adjustment (adjusted odds ratio [aOR] = 1.16, 95% CI .31-4.33, p > .05). PDE was not related to the overall or marijuana/illegal drug experimentation. The likelihood of overall drug experimentation was doubled per SD increase in externalizing problems (aOR = 2.28, 95% CI 1.33-3.91, p = .003) and, among girls, 2.82 times greater (aOR = 2.82, 95% CI 1.34-5.94, p = .006) per SD increase in internalizing problems. Age and perceived peer drug use were significant covariates.

conclusionsDrug experimentation was relatively common (50%), especially in the context of externalizing problems, internalizing problems (girls only), older age, and perceived peer drug use. Findings support the Problem Behavior Theory and suggest that adolescent drug prevention addresses behavioral problems and promotes prosocial peer groups.

Indexed as

Black or African AmericanPrenatal Exposure Delayed EffectsAdolescentAdultCase-Control StudiesFemaleHumansMaleMarylandMental DisordersPregnancyProspective StudiesSubstance-Related DisordersUrban PopulationBehavioral problemsDrug experimentationGenderPrenatal drug exposure

Identifiers

PMID24768161
PMCPMC4752830
OpenAlexW2071457177

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.