ReviewParkinsonism & related disorders2014
Restless legs syndrome and pregnancy: a review.
Review in Parkinsonism & related disorders, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07144631 (PENS-P), which is not on this map. Cited by 31 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
PENS-P: Peroneal Electrical Nerve Stimulation in Pregnancy for Restless Legs Syndrome (RLS)
Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it, 91 citations in OpenAlex.
- Prevalence and factors associated with restless legs syndrome among pregnant women in middle-income countries: a systematic review and meta-analysis.Frontiers in medicine · 2023Pooled it
- Effect of dairy products fortified with vitamin dBMC women's health · 2024Trial
- The Effect of Clonazepam on Restless Legs Syndrome in a Pregnant Woman: A Case Report of a Patient with Six Previous Pregnancies Accompanied by This Syndrome.Journal of clinical medicine · 2026Article
- Sleep Disturbances and Their Correlates in Essential Tremor and Essential Tremor Plus: A Questionnaire-Based Case-Control Study.Tremor and other hyperkinetic movements (New York, N.Y.) · 2026Article
- Restless legs syndrome among third-trimester pregnant women attending ANC Clinic in public hospitals in North Wollo Zone, Ethiopia.PloS one · 2026Article
- Lifestyle medicine pillars for women's heart health.American journal of preventive cardiology · 2025Article
- The Critical Role of Iron in Pregnancy, Puerperium, and Fetal Development.Journal of clinical medicine · 2025Review
- Clinical profile of restless leg syndrome and its effect on sleep and quality of life.Journal of family medicine and primary care · 2025Article
- Article
- Sleep Disorders in Women: What Should a Gynecologist Know?Geburtshilfe und Frauenheilkunde · 2024Article
- Evaluation of the relationship between restless legs syndrome, mental status, and sleep disorders among Moroccan women during their third trimester of pregnancy.Annals of medicine and surgery (2012) · 2024Article
- Sleep pattern and disorders among pregnant women in Ibadan, Southwest Nigeria.BMC women's health · 2024Article
- New-onset movement disorder in the immediate postpartum period.BMJ case reports · 2023Article
- The Prevalence, Severity, and Predictive Factors of Restless Legs Syndrome in Pregnancy.Cureus · 2023Article
- Phenotypical predictors of pregnancy-related restless legs syndrome and their association with basal ganglia and the limbic circuits.Scientific reports · 2021Article
- Zinc and Magnesium Levels of Pregnant Women with Restless Leg Syndrome and Their Relationship with Anxiety: A Case-Control Study.Biological trace element research · 2021Article
- Unraveling the Mysteries of Restless Leg Syndrome.Cureus · 2020Review
- Restless Legs Syndrome During Pregnancy and 12 Weeks Postpartum and its Links to Cardiovascular Diseases, Stressful Life Events, and Psychiatric History.Journal of clinical medicine · 2020Article
- Sleep quality and restless leg syndrome among antenatal women attending government healthcare facilities in urban bangalore.Journal of family medicine and primary care · 2020Article
- Restless Legs Syndrome in Pregnant Thai Women: Prevalence, Predictive Factors, and Natural Course.Journal of clinical neurology (Seoul, Korea) · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 3 countries.
Funding
Abstract
Restless legs syndrome (RLS) is a common sensorimotor neurological disorder that is diagnosed according to the revised criteria of the International RLS Study Group (IRLSSG). The pathophysiology of RLS is still unknown and its prevalence is influenced by ethnicity, age, and gender. RLS is divided into two types by etiology: primary or idiopathic and secondary. Primary RLS is strongly influenced by a genetic component while secondary RLS is caused by other associated conditions such as end-stage renal disease or peripheral neuropathy. Another common condition associated with RLS is pregnancy. The prevalence of RLS during pregnancy is two to three times higher than in the normal population and is influenced by the trimester and the number of parity. The main mechanisms that may contribute to the pathophysiology of RLS during pregnancy are hormonal changes and iron and folate status. Standard medications for treating RLS during pregnancy are not established. Most medications have been used according to the evidence from non-pregnant patients. Therefore, consideration of the medical treatment for treating RLS during pregnancy should be balanced between the benefit of relieving the symptoms and maternal and fetal risk. In general, the prognosis of RLS during pregnancy is good and symptoms are usually relieved after delivery.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.