Evidence map›Paper›PMID 24767487›Full record

ReviewProgress in brain research2014

Cortical odor processing in health and disease.

Donald A Wilson, Wenjin Xu, Benjamin Sadrian, Emmanuelle Courtiol, Yaniv Cohen, Dylan C Barnes

Abstract readReview
In one paragraph

Review in Progress in brain research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Gene expression and gray matter volume changes in Post-COVID-19 olfactory dysfunction: a transcriptomic-neuroimaging study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
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  8. Review
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  16. Retinorecipient areas in the common marmoset (Frontiers in neural circuits · 2023
    Review
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  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Donald A WilsonEmotional Brain Institute, Nathan Kline Institute for Psychiatric Research, New York, USA; Department of Child and Adolescent Psychiatry, New York University Langone School of Medicine, New York, USA; Cognitive Neuroscience Program, City College, City University of New York, New York, USA. Electronic address: donald.wilson@nyumc.org.
Wenjin XuEmotional Brain Institute, Nathan Kline Institute for Psychiatric Research, New York, USA; Department of Child and Adolescent Psychiatry, New York University Langone School of Medicine, New York, USA.
Benjamin SadrianEmotional Brain Institute, Nathan Kline Institute for Psychiatric Research, New York, USA; Department of Child and Adolescent Psychiatry, New York University Langone School of Medicine, New York, USA.
Emmanuelle CourtiolEmotional Brain Institute, Nathan Kline Institute for Psychiatric Research, New York, USA; Department of Child and Adolescent Psychiatry, New York University Langone School of Medicine, New York, USA.
Yaniv CohenEmotional Brain Institute, Nathan Kline Institute for Psychiatric Research, New York, USA; Department of Child and Adolescent Psychiatry, New York University Langone School of Medicine, New York, USA.
Dylan C BarnesEmotional Brain Institute, Nathan Kline Institute for Psychiatric Research, New York, USA; Department of Child and Adolescent Psychiatry, New York University Langone School of Medicine, New York, USA; Cognitive Neuroscience Program, City College, City University of New York, New York, USA.

Funding

CORTICAL PROCESSING OF OLFACTORY STIMULIR01DC003906 · NIDCD · UNIVERSITY OF OKLAHOMA NORMAN · PI WILSON, DONALD A · 1999 to 2017
$4.2M
Modulation of Olfactory Sensory Function by Amyloid-betaR01AG037693 · NIA · NATHAN S. KLINE INSTITUTE FOR PSYCH RES · PI LEVY, EFRAT, NIXON, RALPH A. · 2011 to 2015
$1.6M
NIA NIH HHS R01 AG037693NIDCD NIH HHS R01 DC003906
6 · The paper itself

Abstract

The olfactory system has a rich cortical representation, including a large archicortical component present in most vertebrates, and in mammals neocortical components including the entorhinal and orbitofrontal cortices. Together, these cortical components contribute to normal odor perception and memory. They help transform the physicochemical features of volatile molecules inhaled or exhaled through the nose into the perception of odor objects with rich associative and hedonic aspects. This chapter focuses on how olfactory cortical areas contribute to odor perception and begins to explore why odor perception is so sensitive to disease and pathology. Odor perception is disrupted by a wide range of disorders including Alzheimer's disease, Parkinson's disease, schizophrenia, depression, autism, and early life exposure to toxins. This olfactory deficit often occurs despite maintained functioning in other sensory systems. Does the unusual network of olfactory cortical structures contribute to this sensitivity?

Indexed as

SmellAnimalsCerebral CortexHumansOdorantsOlfaction DisordersOlfactory PathwaysOlfactory Perceptionentorhinal cortexmediodorsal thalamusodor perceptionorbitofrontal cortexpiriform cortex

Identifiers

PMID24767487
PMCPMC4284974

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.